AQR
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Official Full Name
aquarius homolog (mouse)
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Synonyms
AQR; aquarius homolog (mouse); intron-binding protein aquarius; fSAP164; functional spliceosome associated protein 164; KIAA0560; intron-binding protein of 160 kDa; functional spliceosome-associated protein 164; IBP160; DKFZp686B23123;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | AQR-2585H | Recombinant Human AQR Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | AQR-1828H | Recombinant Human AQR Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Mouse | Aqr-822M | Recombinant Mouse Aqr Protein, MYC/DDK-tagged | HEK293T | MYC/DDK | ||
Zebrafish | AQR-10765Z | Recombinant Zebrafish AQR | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- AQR Related Articles
AQR involved in several pathways and played different roles in them. We selected most pathways AQR participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AQR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Spliceosome | THOC2;SNRPF;HSPA6;SRSF2A;HSP70;U2AF2B;DDX39B;HNRNPC;BUD31 |
AQR has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by AQR itself. We selected most functions AQR had, and list some proteins which have the same functions with AQR. You can find most of the proteins on our site.
Function | Related Protein |
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AQR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AQR here. Most of them are supplied by our site. Hope this information will be useful for your research of AQR.
- Q&As
- Reviews
Q&As (23)
Ask a questionGiven its involvement in ribosome biogenesis, targeting the AQR protein or related pathways could potentially have therapeutic implications in disorders associated with aberrant ribosome assembly and protein synthesis. However, further investigation is needed to develop specific interventions.
Yes, the AQR protein is highly conserved across various species, including humans, mice, and yeast. This conservation indicates its importance in fundamental cellular processes.
Yes, as the AQR protein is crucial for ribosome biogenesis, any disturbances or mutations in the AQR gene or protein can disrupt normal cellular processes dependent on proper protein synthesis. This can potentially impact various cellular functions and lead to developmental or health issues.
Yes, as the AQR protein is crucial for ribosome biogenesis, any disturbances or mutations in the AQR gene or protein can disrupt normal cellular processes dependent on proper protein synthesis. This can potentially impact various cellular functions and lead to developmental or health issues.
Mutations in the AQR gene have been found in individuals with syndromic intellectual disability. These mutations weaken the AQR protein's ability to carry out its normal functions, particularly in ribosome assembly, which can result in impaired intellectual development.
Mutations in the AQR gene have been found in individuals with syndromic intellectual disability. These mutations weaken the AQR protein's ability to carry out its normal functions, particularly in ribosome assembly, which can result in impaired intellectual development.
While the primary role of the AQR protein is in ribosome biogenesis, recent studies suggest that it may also play a role in DNA damage response and repair pathways.
Currently, there are no known specific diseases directly linked to alterations in the AQR protein. However, its involvement in ribosome biogenesis suggests potential implications in disorders related to abnormal protein synthesis.
While specific post-translational modifications of the AQR protein have not been extensively studied, it is known that phosphorylation can occur on other ribosomal assembly factors. Further research is needed to determine if the AQR protein undergoes any post-translational modifications.
While specific post-translational modifications of the AQR protein have not been extensively studied, it is known that phosphorylation can occur on other ribosomal assembly factors. Further research is needed to determine if the AQR protein undergoes any post-translational modifications.
Research on the AQR protein is ongoing, particularly regarding its precise role in ribosome biogenesis and its potential involvement in human diseases. Further studies aim to unravel the molecular mechanisms and functional significance of this protein.
Yes, mutations in the AQR gene have been identified in certain individuals with syndromic intellectual disability. These mutations can impair ribosome biogenesis and lead to cellular and developmental abnormalities.
The AQR protein binds to specific regions of rRNA and helps in forming ribosomal subunits by facilitating the incorporation of ribosomal proteins into the rRNA scaffold.
Currently, there are no specific therapeutic interventions targeting the AQR protein. However, understanding its role in ribosome biogenesis may provide insights into potential strategies for addressing disorders related to abnormal protein synthesis in the future.
Currently, there are no specific therapeutic interventions targeting the AQR protein. However, understanding its role in ribosome biogenesis may provide insights into potential strategies for addressing disorders related to abnormal protein synthesis in the future.
The AQR protein is involved in the assembly of ribosomal subunits by helping to incorporate rRNA into the scaffold. It interacts with specific regions of rRNA and facilitates the incorporation of ribosomal proteins, contributing to the formation of functional ribosomes.
The AQR protein is involved in the assembly of ribosomal subunits by helping to incorporate rRNA into the scaffold. It interacts with specific regions of rRNA and facilitates the incorporation of ribosomal proteins, contributing to the formation of functional ribosomes.
Yes, alterations in the AQR protein levels can potentially disrupt ribosome biogenesis, leading to impaired protein synthesis. This can affect the production of essential proteins involved in various cellular processes, ultimately impacting overall protein synthesis.
Yes, alterations in the AQR protein levels can potentially disrupt ribosome biogenesis, leading to impaired protein synthesis. This can affect the production of essential proteins involved in various cellular processes, ultimately impacting overall protein synthesis.
Yes, studies have identified several proteins that interact with the AQR protein during ribosome biogenesis. These include other ribosomal assembly factors, RNA helicases, and proteins involved in pre-rRNA processing.
Yes, studies have identified several proteins that interact with the AQR protein during ribosome biogenesis. These include other ribosomal assembly factors, RNA helicases, and proteins involved in pre-rRNA processing.
While alterations in AQR protein expression levels have not been clearly linked to specific diseases, dysregulation of ribosome assembly factors, including AQR, has been implicated in various cancers and neurodegenerative disorders. Further research is needed to establish direct associations.
While alterations in AQR protein expression levels have not been clearly linked to specific diseases, dysregulation of ribosome assembly factors, including AQR, has been implicated in various cancers and neurodegenerative disorders. Further research is needed to establish direct associations.
Customer Reviews (8)
Write a reviewthe manufacturer can contribute to the research process by providing top-quality AQR protein that meets rigorous standards of purity, stability, and reliability.
This unique capability to selectively bind to exposed PS simplifies the identification and quantification of different cellular populations, reducing experimental errors and enhancing accuracy.
This may include providing detailed protocols, troubleshooting guidance, and access to knowledgeable experts who can answer any inquiries or concerns.
This includes complementary reagents, protocols, and access to an extensive knowledge base, all aimed at streamlining the trial process and maximizing the chances of achieving meaningful results.
They can provide technical assistance, ensuring optimal utilization of the product.
By choosing the AQR protein and partnering with the manufacturer, researchers can confidently conduct their trials, achieve reliable results, and contribute to groundbreaking discoveries.
the AQR protein demonstrates exceptional stability, allowing for prolonged storage and usage without compromising its integrity.
The manufacturer of the AQR protein plays a crucial role in supporting researchers during their trials.
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