ARRDC4
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Official Full Name
arrestin domain containing 4
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Synonyms
ARRDC4;arrestin domain containing 4;28087;ENSG00000140450;15q26.3;FLJ36045;arrestin domain-containing protein 4;arrestin domain-containing protein 4;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ARRDC4-859H | Recombinant Human ARRDC4 protein, GST-tagged | Wheat Germ | GST | ||
Human | ARRDC4-1504HF | Recombinant Full Length Human ARRDC4 Protein, GST-tagged | In Vitro Cell Free System | GST | 418 amino acids | |
Rat | ARRDC4-805R | Recombinant Rat ARRDC4 Protein | Mammalian Cell | His | ||
Rat | ARRDC4-461R-B | Recombinant Rat ARRDC4 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | ARRDC4-461R | Recombinant Rat ARRDC4 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
- ARRDC4 Related Articles
ARRDC4 involved in several pathways and played different roles in them. We selected most pathways ARRDC4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARRDC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ARRDC4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ARRDC4 itself. We selected most functions ARRDC4 had, and list some proteins which have the same functions with ARRDC4. You can find most of the proteins on our site.
Function | Related Protein |
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ARRDC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARRDC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARRDC4.
- Q&As
- Reviews
Q&As (12)
Ask a questionARRDC4 is known to interact with several proteins and participate in various protein-protein interaction networks. It has been reported to interact with G protein-coupled receptors (GPCRs), components of the endocytic machinery, and signaling molecules involved in receptor internalization and trafficking.
Yes, ARRDC4 can undergo post-translational modifications such as phosphorylation, ubiquitination, and acetylation. These modifications can regulate its stability, activity, and protein-protein interactions.
As of now, there are no known drugs specifically targeting ARRDC4. However, ongoing research or drug discovery efforts may identify compounds that can modulate its function or interactions in the future.
There is evidence to suggest that the expression of ARRDC4 can be altered during disease progression or under pathological conditions. For example, aberrant expression of ARRDC4 has been observed in certain cancers and cardiovascular diseases, indicating its potential role in disease pathogenesis.
ARRDC4 expression and activity can be regulated by specific stimuli or signaling pathways. For example, phosphorylation events mediated by protein kinases can modulate its function and localization in response to specific stimuli.
Yes, accumulating evidence suggests that ARRDC4 may play a role in certain human diseases or disorders. Studies have implicated its involvement in the pathogenesis of cancers, cardiovascular diseases, neurological disorders, and autoimmune conditions.
ARRDC4 can be found in multiple cellular compartments depending on the context. It has been observed in the cell membrane, endosomes, lysosomes, and cytoplasm. Its subcellular localization can vary based on the specific cellular processes it is involved in.
ARRDC4 is expressed in various tissues and cell types. mRNA expression profiling and immunohistochemistry studies have shown its presence in the brain, heart, liver, kidney, and immune cells.
Yes, ARRDC4 can modulate intracellular signaling pathways, particularly those involving GPCRs. It has been shown to regulate receptor internalization, desensitization, and recycling, thereby influencing downstream signaling events.
The presence of genetic variants or mutations in ARRDC4 associated with diseases has not been extensively explored. Genetic association studies or sequencing analyses may reveal any potential links between ARRDC4 genetic variations and disease susceptibility or progression.
The involvement of ARRDC4 in embryonic development or tissue homeostasis is not well-characterized. Investigating its expression patterns and conducting functional studies in relevant models can provide insights into its potential roles during development and in maintaining tissue equilibrium.
Currently, the diagnostic or prognostic utility of ARRDC4 as a biomarker is not well-established. However, further investigations exploring its expression patterns and associations with disease parameters may elucidate its potential as a biomarker in specific conditions.
Customer Reviews (3)
Write a reviewThe combination of the protein's exceptional characteristics and the manufacturer's outstanding technical assistance equips me with the necessary resources to overcome potential hurdles and achieve groundbreaking results.
By relying on the ARRDC4 protein, I can approach my research with unwavering confidence in its quality and the unparalleled support extended by its manufacturer.
Their expertise and responsiveness exemplify their dedication to assisting customers, offering solutions and guidance whenever challenges arise.
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