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CDK14

Official Full Name

cyclin-dependent kinase 14
Overview

PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 (PubMed;11313143)).
Synonyms

CDK14; cyclin-dependent kinase 14; PFTAIRE protein kinase 1 , PFTK1; PFTAIRE1; hPFTAIRE1; PFTAIRE protein kinase 1; cell division protein kinase 14; serine/threonine-protein kinase PFTAIRE-1; PFTK1; KIAA0834;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell
Sf9 Insect Cell

Tag

GST
His
His (Fc)
Avi
Myc
DDK
Myc|DDK
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CDK14-116H	Active Recombinant Human CDK14/CyclinY, GST-tagged	Sf9 Insect Cell	GST		Inquiry
Human	CDK14-180H	Recombinant Human CDK14, GST-tagged	Sf9 Insect Cell	GST		Inquiry
Human	CDK14-3158H	Recombinant Human CDK14 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	CDK14-725H	Recombinant Human CDK14 Protein, His-tagged	E.coli	N-His	Tyr135-Phe419	Inquiry
Mouse	CDK14-3194M	Recombinant Mouse CDK14 Protein	Mammalian Cell	His		Inquiry
Mouse	CDK14-1517M	Recombinant Mouse CDK14 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	CDK14-1517M-B	Recombinant Mouse CDK14 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Cdk14-4814M	Recombinant Mouse Cdk14 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	CDK14-6824Z	Recombinant Zebrafish CDK14	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

CDK14 involved in several pathways and played different roles in them. We selected most pathways CDK14 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Transcriptional misregulation in cancer	PML;MLL1;TLX1;HMGA2;KDM6A;PROM1;RXRB;CLSTN2;RXRG

CDK14 has several biochemical functions, for example, ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK14 itself. We selected most functions CDK14 had, and list some proteins which have the same functions with CDK14. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	ORC4;TDRD12;ACVR1BA;STK16;CAMK2B;PGK1;RAF1;PTK7A;RIOK2
cyclin binding	PFTK1;CDKN1A;CDK12;USP2;INCA1;PTCH1;MDFIC;CDK2;HDAC3
cyclin-dependent protein serine/threonine kinase activity	CDKL2;CDK9;CDK5R1;CCND3;CDK5;NAT1;CDK14;CDKL3;CDKL4
kinase activity	CSNK1DA;MAP2K2A;GRK1B;SRPK1A;PRKCBB;GRK7A;RIPK4;ACVR1BA;PRKCHA
nucleotide binding	RBM17;STK24B;TOR1L3;HNRNPA1B;ARF3A;TYMS;ATP2B1A;ITPA;APAF1
protein kinase activity	MKNK2A;TSSK1;PTK2AA;TBRG4;PAN3;BUB1B;DCKL1B;MAP3K1;GM711
protein serine/threonine kinase activity	ICK;CDC42BPA;CSNK2A1;TESK2;PRKG1A;CAMK1GA;BMPR2A;PRKCE;PRKCI
transferase activity	TNIKB;SETD1BA;HGSNAT;PKZ;SPS2;C1GALT1A;WEE2;CD38;LASS5

CDK14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK14 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK14.

Ccny

Research Area

Aoshiba, K; Tsuji, T; et al. Senescence-associated secretory phenotype in a mouse model of bleomycin-induced lung injury. EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 65:1053-1062(2013).

Capobianco, G; Marras, V; et al. P16 immunostaining and HPV testing in histological specimens from the uterine cervix. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 34:227-230(2013).