CETN1
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Official Full Name
centrin, EF-hand protein, 1
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Overview
The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. -
Synonyms
CETN1; centrin, EF-hand protein, 1; CETN; centrin-1; CEN1; Caltractin; Caltractin isoform 2; CEN 1; Centrin EF hand protein 1; Centrin1; CETN 1; CETN1_HUMAN; EF hand protein 1; EF-hand protein; OTTHUMP00000162193; calcium binding protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CETN1-6776H | Recombinant Human Centrin, EF-hand Protein, 1, His-tagged | E.coli | His |
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| Human | CETN1-27955TH | Recombinant Human CETN1 | Wheat Germ | N/A | 100 amino acids |
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| Human | CETN1-27954TH | Recombinant Human CETN1 | Wheat Germ | N/A | 79 amino acids |
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| Human | CETN1-1153H | Recombinant Human CETN1 Protein, GST-Tagged | Wheat Germ | GST |
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| Human | CETN1-11128H | Recombinant Human CETN1, GST-tagged | E.coli | GST | 1-172a.a. | |
| Human | CETN1-7562HCL | Recombinant Human CETN1 293 Cell Lysate | HEK293 | N/A |
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| Human | CETN1-3287HF | Recombinant Full Length Human CETN1 Protein, GST-tagged | In Vitro Cell Free System | GST | 172 amino acids |
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| Human | CETN1-4724H | Recombinant Human CETN1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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| Human | CETN1-753H | Recombinant Human CETN1 Protein, His-tagged | E.coli | N-His | Met1-Tyr172 |
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| Mouse | CETN1-3854M |
Recombinant Mouse CETN1 Protein, His-tagged
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E. coli | His | Met1~Glu161 | |
| Mouse | CETN1-3338M | Recombinant Mouse CETN1 Protein | Mammalian Cell | His |
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| Mouse | Cetn1-2126M | Recombinant Mouse Cetn1 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Mouse | CETN1-1606M-B | Recombinant Mouse CETN1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | CETN1-1606M | Recombinant Mouse CETN1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Chicken | CETN1-5252C | Recombinant Chicken CETN1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
CETN1 involved in several pathways and played different roles in them. We selected most pathways CETN1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CETN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
CETN1 has several biochemical functions, for example, G-protein beta/gamma-subunit complex binding, calcium ion binding, heterotrimeric G-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CETN1 itself. We selected most functions CETN1 had, and list some proteins which have the same functions with CETN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein beta/gamma-subunit complex binding | GNAT1;GNAI2B;GNA13;GNAI2A;GNA13B;GNAT2;GNA12;GNAO1B;GNA15.1 |
| calcium ion binding | PLS3;MYL2B;PCDHB1;SWAP70;TESCB;SYT11;PCDHA10;SNCA;CCDC48 |
| heterotrimeric G-protein binding | ADORA1;CETN1;CETN4;ADRA2A;CETN2 |
| microtubule binding | MAP4;RAB11A;KIF7;NUMA1;SKA1;KIF2B;NDRG1;PRNP;MAST2 |
| protein binding | ZNF434;DTX3;TET2;CD44;EML2;BMPR1A;PPP3R1;FCN2;CREB3L3 |
CETN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CETN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CETN1.
SGSM1; POC5; USP49; TBCCD1
- Q&As
- Reviews
Q&As (5)
Ask a questionOne challenge is the need for a deeper understanding of the specific molecular mechanisms and pathways involving CETN1 in disease states.
Certain genetic variations in the CETN1 gene have been linked to ciliopathies and developmental disorders, highlighting the clinical relevance of its genetic variations.
CETN1 is involved in centriole duplication and cell division processes, and its dysregulation can impact cell cycle control.
Various quantitative assays, such as enzyme-linked immunosorbent assay (ELISA) or mass spectrometry, can be used to measure CETN1 protein levels in clinical samples.
Currently, there are limited clinical trials specifically targeting CETN1 protein, but its role in cancer biology is being investigated in various studies.
Customer Reviews (3)
Write a reviewTheir dedicated team of experts is prompt, knowledgeable, and readily available to tackle any hurdles or concerns I may encounter.
By harnessing the power of the CETN1 protein, I can harness its outstanding quality and tap into its potential to obtain dependable and meaningful findings.
Used in protein electron microscopy structure analysis.Great.
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