GABARAPL2
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Official Full Name
GABA(A) receptor-associated protein-like 2
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Overview
Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. -
Synonyms
GABARAPL2; GABA(A) receptor-associated protein-like 2; gamma-aminobutyric acid receptor-associated protein-like 2; ATG8; ATG8C; GATE 16; GATE16; GEF2; ganglioside expression factor 2; MAP1 light chain 3 related protein; MAP1 light chain 3-related protein;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E. coli
- E.coli
- HEK293
- Human Cell
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- GABARAPL2 Related Research Area
GABARAPL2 involved in several pathways and played different roles in them. We selected most pathways GABARAPL2 participated on our site, such as Cellular responses to stress, FoxO signaling pathway, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABARAPL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Cellular responses to stress | DNAJB6;POT1A;AGO1;MAP1LC3C;ATG4A;CDKN2B;HIF1AL;AMBRA1A;C7orf59 |
FoxO signaling pathway | KLF2B;IRS2;IL7R;PIK3R3A;STAT3;PDPK1B;MAPK12A;FOXO6;AKT2 |
GABAergic synapse | SRC;GABRA1;SLC38A3;NSF;PLCL1;SLC6A1;GABRG3;GABRR2;GNG10 |
Macroautophagy | GABARAPL2;WDR45L;RB1CC1;ULK1A;ATG9A;ATG9B;DYNLL2B;ATG101;ATG4A |
Regulation of autophagy | IFNPHI1;ATG12;ATG4B;ATG14;ATG5;IFNA4;Ifna11;INS;GABARAPL1 |
Senescence and Autophagy | SLC39A2;GABARAP;UVRAG;RB1CC1;SLC39A3;IGFBP5;ING2;MAP1LC3B;GABARAPL2 |
GABARAPL2 has several biochemical functions, for example, ATPase binding, GABA receptor binding, SNARE binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GABARAPL2 itself. We selected most functions GABARAPL2 had, and list some proteins which have the same functions with GABARAPL2. You can find most of the proteins on our site.
Function | Related Protein |
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ATPase binding | TAF9;RAB4A;ATP6V0A2B;PEX26;FXYD7;SLC26A9;SDF2L1;SVIP;ANK1 |
GABA receptor binding | AKAP5;PPP2CA;MAF1;GABRA5;PLCL1;GABARAPL1;PLCL2;GABRB1;GABRG1 |
SNARE binding | STX4A;STX7;STX11A;VAMP8;STX3A;SNAPIN;MYO5A;STX11B.1;SYBL1 |
beta-tubulin binding | GABARAPL1;GABARAP;HTT;RANBP10;GABARAPL2;EMD;ARL8B;CASC1;SERPINB1A |
microtubule binding | TUBGCP5;FNTA;FMN1;HDAC6;AKAP1;SYBU;POLB;JAKMIP2;GOLGA2 |
protein binding | PARP1;FBXL12;PLXDC1;PLEKHH2;MB21D2;SIT1;ZCCHC10;TRIM9;NEDD4L |
ubiquitin protein ligase binding | PRKAR2A;AXIN2;RAD18;CUL5;FZD5;UBE2W;CXCR4;FOXO1;RPA3 |
GABARAPL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABARAPL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GABARAPL2.
SQSTM1; UBA5
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