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GZF1

Official Full Name

GDNF-inducible zinc finger protein 1
Overview

GZF1 has been identified as a gene whose expression is induced by a neurotrophic factor, GDNF. It codes a protein which has BTB/POZ domain in its N-terminal region and 10 of zinc finger motifs in its C-terminal area from the center. It has been known by performance analysis that GZF1 is a transcriptional repression factor which sequence-specifically binds to DNA and the binding sequence is present in transcription control region of HOXA10.
Synonyms

GZF1; GDNF-inducible zinc finger protein 1; zinc finger protein 336 , ZNF336; dJ322G13.2; ZBTB23; zinc finger protein 336; zinc finger and BTB domain-containing protein 23; ZNF336;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

HEK293
In Vitro Cell Free System
Insect Cell
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Strep
No tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GZF1-4515H	Recombinant Human GZF1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GZF1-3385HF	Recombinant Full Length Human GZF1 Protein, GST-tagged	In Vitro Cell Free System	GST	711 amino acids	Inquiry
Human	GZF1-1280H	Recombinant Human GZF1 Protein (E2-E711), His/Strep tagged	Insect Cell	His/Strep	E2-E711	Inquiry
Human	GZF1-1279H	Recombinant Human GZF1 Protein (E2-E711), Tag Free	Insect Cell	No tag	E2-E711	Inquiry
Mouse	GZF1-7409M	Recombinant Mouse GZF1 Protein	Mammalian Cell	His		Inquiry
Mouse	GZF1-4023M-B	Recombinant Mouse GZF1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	GZF1-4023M	Recombinant Mouse GZF1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	GZF1-2770R	Recombinant Rat GZF1 Protein	Mammalian Cell	His		Inquiry
Rat	GZF1-2424R	Recombinant Rat GZF1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	GZF1-2424R-B	Recombinant Rat GZF1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

GZF1 involved in several pathways and played different roles in them. We selected most pathways GZF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GZF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

GZF1 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GZF1 itself. We selected most functions GZF1 had, and list some proteins which have the same functions with GZF1. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	FOXN4;ZNF317;H1FNT;PHC2;ZBTB43;DEAF1;PURBB;DEDD2;SOX3
RNA polymerase II core promoter proximal region sequence-specific DNA binding	E2F4;ZNF257;CLOCK;ASCL1;BATF3;NKX2-8;EN1;RBPJ;PLAG1
RNA polymerase II distal enhancer sequence-specific DNA binding	CREB1;PAX4;NFATC1;H3F3B;MED12;NR5A2;HOXB5;PBX3;BACH1
metal ion binding	ZSCAN23;NLN;NSF;ZFP526;STEAP3;MECOM;PDE7A;GLRX5;CDKAL1
nucleic acid binding	YTHDC2;REV3L;Akap17b;GPATCH2;EXOG;GRSF1;ZNFL2A;RNASE11;ZFP710
sequence-specific DNA binding	NKX2.5;ZFP13;FOXA3;POU2F1;FOXC2;HOXC6A;SALL3B;TFAP4;HOXB6A
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	NFATC2;ZGPAT;GCFC2;NFIL3-2;SALL1;CUX2;E2F8;ATF7;KLF16
transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding	ARX;BACH2;GZF1;PROP1;MSC;ZBTB16;BACH1;PAX4

GZF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GZF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GZF1.