Ins2
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Official Full Name
insulin 2
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Synonyms
INS2;insulin 2;insulin-2;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- Myc
- DDK
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Mouse | INS2-8234M | Recombinant Mouse INS2 Protein | Mammalian Cell | His |
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| Mouse | INS2-4561M | Recombinant Mouse INS2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | Ins2-3551M | Recombinant Mouse Ins2 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Mouse | INS2-4561M-B | Recombinant Mouse INS2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | Ins2-4180M | Recombinant Mouse Ins2 protein, His&Myc-tagged | E.coli | His&Myc | 25-110aa |
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| Rat | INS2-3077R | Recombinant Rat INS2 Protein | Mammalian Cell | His |
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| Rat | INS2-2733R-B | Recombinant Rat INS2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | INS2-2733R | Recombinant Rat INS2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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- Involved Pathway
- Protein Function
- Interacting Protein
Ins2 involved in several pathways and played different roles in them. We selected most pathways Ins2 participated on our site, such as Ras signaling pathway, Rap signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ins2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ras signaling pathway | PLA2G12B;SHOC2;FGF10;PLA2G6;RASAL1;PLA2G12A;RASGRP3;Fasl;AKT1 |
| Rap signaling pathway | ANGPT1;FGF14;FGF5;F2R;LPAR4;FLT1;GRIN1;FGF2;CALM4 |
| cGMP-PKG signaling pathway | ATP1B2;PLN;PRKG1;INS1;PIK3R2;GNAI2;Adcy4;CREB3L1;SLC25A5 |
| HIF- signaling pathway | ENO2;HK1;ANGPT4;NOS2;MAPK3;RPS6KB2;LTBR;IGF1R;MKNK2 |
| FoxO signaling pathway | RAF1B;MAPK3;G6PC3;SMAD4;TGFBR1A;PRKAB1B;TGFB1A;SOD2;CCNG2 |
| Phospholipase D signaling pathway | PDGFC;IL-8;INS;PIK3R1;FCER1A;AKT1;AKT2;PLA2G4F;KRAS |
| Oocyte meiosis | PPP2R1B;MAP2K1;SPDYA;PPP2R5B;PGR;CCNB1;RPS6KA3A;Ar;CAMK2G1 |
| Regulation of autophagy | PRKAA2;IFNA14;IFNA10;PRKAA1;PIK3R4;Ifna11;IFNA1;IFNA21;ATG5 |
| mTOR signaling pathway | ULK3;RRN3;EIF4E1C;IGF1;STRADA;IRS1;PIK3R3A;PIK3R2;RPS6KAL |
| PIK-Akt signaling pathway | ANGPT4;KIT;FGF1;YWHAH;GRB2;FGF7;IFNA7;GNG2;PKN3 |
| AMPK signaling pathway | GYS2;SLC2A4;PFKFB1;PIK3R2;PPP2R5C;PCK1;IGF1;ELAVL1;PCK2 |
| Regulation of actin cytoskeleton | PIK3R5;FGFR4;PIP4K2C;CYFIP1;PIP5K1A;WASB;ARHGEF7;HRASA;ITGAX |
| Insulin signaling pathway | PHKG1A;AKT3A;FLOT2A;PRKAA1;G6PCA.1;EIF4E1C;PYGMA;CALM2A;MKNK2B |
| Insulin secretion | PLCB2;ATP1B3;ATP1A2;FFAR1;ITPR3;FXYD2;TRPM4;KCNMB1;KCNMB2 |
| Ovarian steroidogenesis | HSD3B2;PLA2G4A;LHCGR;PLA2G4F;Adcy4;INS;ACOT2;PRKACB;PRKACA |
| Progesterone-mediated oocyte maturation | CCNB2;GNAI2A;CCNB3;CDC23;GNAI3;CPEB2;PRKACA;BRAF;CDC26 |
| Prolactin signaling pathway | PPIB;KRAS;CCND2;ESR2;GALT;SHC2;CSH;RAF1;PRLR |
| Regulation of lipolysis in adipocytes | ABHD5;PIK3CG;PLIN1;IRS2;INS2;IRS1;Adcy4;GNAI3;PIK3R5 |
| Type II diabetes mellitus | INS-IGF2;SOCS4;PDX1;PIK3CA;MAPK10;MTOR;SLC2A2;ADIPOQ;PIK3CG |
| Insulin resistance | CREB3L1;PDPK1B;SLC2A4;GFPT1;PPP1CBL;PRKAB1B;SLC27A1B;NFKBIAA;AKT3A |
| Non-alcoholic fatty liver disease (NAFLD) | BAX;PIK3R2;NDUFV3;UQCR11;COX7A2;NFKB1;IRS2;COX7B;NDUFB11 |
| Type I diabetes mellitus | IL12B;Il2;GZMB;IL12A;LTA;HLA-DRB1;HLA-G;ICA1;TNF |
| Maturity onset diabetes of the young | NKX6;HNF1B;FOXA3;HNF1A;PKLR;MNX1;HES1;ONECUT1;FOXA2 |
| Aldosterone-regulated sodium reabsorption | SGK1;ALPHA-ENAC;IGF1;ATP1B1;ATP1A4;PRKCG;PIK3CD;PIK3R5;INS2 |
| Prostate cancer | NOXA1;SMARCC2;IKBKG;CCND1;NKX3-1;RELA;MTOR;GRB2;BRAF |
Ins2 has several biochemical functions, for example, hormone activity, identical protein binding, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ins2 itself. We selected most functions Ins2 had, and list some proteins which have the same functions with Ins2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hormone activity | IGF2;POMCB;CSH1;UCN3;UTS2D;ADIPOQ;CCL25;FAM132A;C19orf80 |
| identical protein binding | RILPL2;KHDC1A;DAPK3;VWA2;KCNH2;TRP53;CALCA;SOD2;P2RX6 |
| insulin receptor binding | INSL3;IRS2;GRB10;PTPN1;DOK7;SNX2;IGF1;DOK6;SHC1 |
| insulin-like growth factor receptor binding | IRS1;SOCS2;IGF2;GNAS;ARRB1;YWHAH;IGF2A;INSR;Ren1 |
| protease binding | TNFRSF10A;SERPINB13;TYSND1;TRIP4;ITGA3;TNF;TRP53;BCL2;ELANE |
| protein complex binding | C8B;CDK5RAP2;CD2AP;NR0B2;TAPBPL;NFYB;MYO7A;PRKACA;UGT1A6A |
Ins2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ins2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ins2.
- Q&As
- Reviews
Q&As (7)
Ask a questionINS2 plays a key role in regulating blood glucose levels.
INS2 consists of 110 amino acids.
INS2 is predominantly synthesized in the beta cells of the pancreas.
INS2 shares similar functions with INS1 in regulating glucose metabolism.
INS2 secretion increases in response to elevated blood glucose levels.
INS2 is stored in secretory granules within beta cells.
The INS2 protein is encoded by the INS2 gene.
Customer Reviews (3)
Write a reviewConsistently achieving specific outcomes validated the pivotal role of the product in our research studies.
The product's cost-effectiveness and clear instructions were instrumental in our experimental design.
The value derived from the product's usage made the investment worthwhile, considering the insights acquired.
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