KLHDC3
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Official Full Name
kelch domain containing 3
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Overview
The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2 (RAG2), a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to express specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasma and meiotic chromatin, which suggests that this gene may be involved in meiotic recombination. Alternatively spliced transcript variants have been found. -
Synonyms
KLHDC3; kelch domain containing 3; kelch domain-containing protein 3; dJ20C7.3; hPeas; PEAS; KLDC3_HUMAN; Protein Peas; RP1-20C7.3; Testis intracellular mediator protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Insect Cell
- Mammalian Cell
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | KLHDC3-405H | Recombinant Human KLHDC3 Protein, His&Myc-tagged | E.coli | His&Myc | 1-382aa | |
Human | KLHDC3-4921HCL | Recombinant Human KLHDC3 293 Cell Lysate | HEK293 | N/A | ||
Human | KLHDC3-2336H | Recombinant Human KLHDC3 protein, His&Myc-tagged | Insect Cell | His&Myc | 1-382aa | |
Mouse | KLHDC3-8693M | Recombinant Mouse KLHDC3 Protein | Mammalian Cell | His | ||
Mouse | Klhdc3-3705M | Recombinant Mouse Klhdc3 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | KLHDC3-4845M-B | Recombinant Mouse KLHDC3 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | KLHDC3-4845M | Recombinant Mouse KLHDC3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | KLHDC3-3275R | Recombinant Rat KLHDC3 Protein | Mammalian Cell | His | ||
Rat | KLHDC3-2931R | Recombinant Rat KLHDC3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | KLHDC3-2931R-B | Recombinant Rat KLHDC3 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | KLHDC3-12462Z | Recombinant Zebrafish KLHDC3 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- KLHDC3 Related Articles
KLHDC3 involved in several pathways and played different roles in them. We selected most pathways KLHDC3 participated on our site, such as IRE1alpha activates chaperones, Metabolism of proteins, Unfolded Protein Response (UPR), which may be useful for your reference. Also, other proteins which involved in the same pathway with KLHDC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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IRE1alpha activates chaperones | FKBP14;KLHDC3;WIPI1;HDGF;SEC63;CXXC1;ADD1;TPP1;YIF1A |
Metabolism of proteins | MTX1;DPAGT1;ST6GALNAC1.2;SLC25A13;TRAPPC2;SMC6;SERPINA7;SEC22A;YY2 |
Unfolded Protein Response (UPR) | KLHDC3;C19orf10;SEC63;CTDSP2;HDGF;PDIA6;WIPI1;DDX11;ASNA1 |
XBP1(S) activates chaperone genes | CTDSP2;CXXC1;FKBP14;WIPI1;TPP1;HDGF;KLHDC3;ASNA1;KDELR3 |
KLHDC3 has several biochemical functions, for example, chromatin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLHDC3 itself. We selected most functions KLHDC3 had, and list some proteins which have the same functions with KLHDC3. You can find most of the proteins on our site.
Function | Related Protein |
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chromatin binding | NKX2-5;ASF1A;GATA2A;L3MBTL1;MEIS3;APBB1;ESR1;EZH2;TAL1 |
protein binding | GFM2;GSK3A;IFNA4;CCDC67;PPP2R2C;FAM50B;PRDM5;STXBP4;OS9 |
KLHDC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLHDC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLHDC3.
DLG3; UBXN7; CSNK1E
- Q&As
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