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LTN1

Official Full Name

listerin E3 ubiquitin protein ligase 1
Overview

Like most RING finger proteins, LTN1 functions as an E3 ubiquitin ligase (Chu et al., 2009 (PubMed 19196968)).
Synonyms

LTN1; listerin E3 ubiquitin protein ligase 1; C21orf10, C21orf98, chromosome 21 open reading frame 98 , ring finger protein 160 , RNF160, zinc finger protein 294 , ZNF294; E3 ubiquitin-protein ligase listerin; FLJ11053; KIAA0714; LISTERIN; ri;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	LTN1-9355M	Recombinant Mouse LTN1 Protein	Mammalian Cell	His	Inquiry
Mouse	LTN1-5241M	Recombinant Mouse LTN1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	LTN1-5241M-B	Recombinant Mouse LTN1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

LTN1 involved in several pathways and played different roles in them. We selected most pathways LTN1 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with LTN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Adaptive Immune System	FGF8B;RNF111;KLRB1F;ICAM4;DYNC1H1;RNF19B;SH2D1B;FCGR1B;KIR2DS2
Antigen processing: Ubiquitination &amp	DZIP3;LRR1;ASB2;RNF4;PJA2;LTN1;SPSB4;SPSB1;RNF182
Proteasome degradation	TRIM11;KLHL21;TPP2;SPSB4;WWP1;RNF220;NPEPPS;RBCK1;STUB1
Class I MHC mediated antigen processing &amp	KLHL20;UBR2;HECTD3;B2ML;ASB11;UBA5;RNF14;SPSB2;ARIH2
presentation	LRR1;DZIP3;RNF111;TRIM9;UBE2V2;GAN;DTX3L;LRSAM1;ASB13
Immune System	DEFB106A;PVRL2L;KIF5B;TRIM62;DEFA3;DHX9;PJA2;TAX1BP1;NLRP4

LTN1 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LTN1 itself. We selected most functions LTN1 had, and list some proteins which have the same functions with LTN1. You can find most of the proteins on our site.

Function	Related Protein
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity	HERC2;RNF144AA;RFWD2;LTN1;ZNRF3;MGRN1A;MARCH9;TMEM129;HECW2
coenzyme F420-0 gamma-glutamyl ligase activity	TRIM71;MARCH9;DTX1;RC3H2;MARCH6;ARIH1L;RNF144AB;SIAH2L;HERC2
coenzyme F420-2 alpha-glutamyl ligase activity	ARIH1L;MARCH11;TMEM129;DTX1;HERC2;TRIM50;MARCH6;RNF180;TRIM41
ligase activity	SIAH1;SH3RF1;PRPF19;RTCD1;HERC2;ITCH;RNF4;SH3RF2;NAPRT
metal ion binding	NEK3;S100A10B;DNAJA3B;GNAI2;HIVEP2A;HDDC3;ZNF581;ZFP354A;ADARB1
protein-glutamic acid ligase activity	DTX1;ZNRF2B;RNF144AB;RNF144AA;RNF180;MARCH4;RNF149;MUL1A;UBE2IA
protein-glycine ligase activity	RNF149;NEURL3;MARCH6;MARCH5L;RNF169;MARCH11;RNF180;MUL1A;MYLIPB
protein-glycine ligase activity, elongating	ZNRF2B;RNF169;SIAH2L;ITCHA;RNF144AB;TRIM71;DTX1;SHRPRBCK1R;MGRN1A
protein-glycine ligase activity, initiating	NEURL1B;RNF169;TRIM41;UBE2IB;RFWD2;MARCH11;NEURL3;ITCHA;RC3H2
ribosomal S6-glutamic acid ligase activity	RNF144AA;MYLIPA;SIAH2L;MARCH11;HERC2;UBE2M;ARIH1L;RAG1;NEURL1B
tubulin-glutamic acid ligase activity	MARCH5L;MARCH6;RFWD2;MGRN1A;NEURL3;RC3H2;TRIM71;RNF187;RNF144AA
tubulin-glycine ligase activity	MARCH4;UBE2IB;RC3H2;TRIM41;DTX1;HECW2;UBE2IA;ZNRF3;UBR1
ubiquitin protein ligase activity	RNF4;UBE2B;ZNRF2;NEDD4L;AMFR;RNF139;UBE2Z;TRIM37;UBE3A
ubiquitin-protein transferase activity	RNF20;RNF125;UBE3C;TRIM32;UHRF1;HUWE1;XIAP;UBE2D2A;FEM1A
zinc ion binding	DNPEP;OAS2;MTA2;FBXO11A;RBM5;MARCH1;TRAF1;ADH8A;ZNF8

LTN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LTN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LTN1.