MID2
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Official Full Name
midline 2
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Overview
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms. -
Synonyms
MID2; midline 2; probable E3 ubiquitin-protein ligase MID2; FXY2; RNF60; TRIM1; Midin-2; Midline defect 2; Midline-2; RING finger protein 60; Ring finger protein protein 60; TRIM1_HUMAN; Tripartite motif protein 1; Tripartite motif-containing protein 1; midin 2; OTTHUMP00000023816; OTTHUMP00000023817;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- E.coli
- HEK293
- In Vitro Cell Free System
- Wheat Germ
- GST
- N/A
- N
- His
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | MID2-877H | Recombinant Human MID2, GST-tagged | E.coli | GST | C-term-350aa | |
Human | MID2-4318HCL | Recombinant Human MID2 293 Cell Lysate | HEK293 | N/A | ||
Human | MID2-4319HCL | Recombinant Human MID2 293 Cell Lysate | HEK293 | N/A | ||
Human | MID2-6588HF | Recombinant Full Length Human MID2 Protein, GST-tagged | In Vitro Cell Free System | GST | 685 amino acids | |
Human | MID2-5330H | Recombinant Human MID2 Protein, GST-tagged | Wheat Germ | GST | ||
Human | MID2-2443H | Recombinant Human MID2 Protein, His-tagged | E.coli | N-His | Ser7-Glu258 |
- Involved Pathway
- Protein Function
- Interacting Protein
- MID2 Related Articles
MID2 involved in several pathways and played different roles in them. We selected most pathways MID2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MID2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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MID2 has several biochemical functions, for example, ligase activity, microtubule binding, phosphoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MID2 itself. We selected most functions MID2 had, and list some proteins which have the same functions with MID2. You can find most of the proteins on our site.
Function | Related Protein |
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ligase activity | UBE2NA;PARK2;RAD18;PET112L;TTLL4;TTC3;TRAF7;ACSF2;ZNRF1 |
microtubule binding | MAPRE1B;LC3;FGF13;KIF12;RCC2;POLB;GAS2L1;KLC3;HAUS8 |
phosphoprotein binding | PIH1D1;RRAGA;SRC;TRPV1;FKBP4;SAG;PRKCSH;IGF2R;SERPINB1A |
protein binding | SLC25A4;ZCCHC13;UTP3;NR0B1;CEP55;BEGAIN;PARVA;FAM50B;PDGFRA |
protein heterodimerization activity | DRD1A;HIST1H2BE;HIST1H2BP;CHRNB4;CUL3;SOX15;EPAS1;MEIS1;PBX1 |
protein homodimerization activity | GSTM3;NR4A3;JAM3;ADRB2;RAG1;ADH5;GSTZ1;SETMAR;ATPIF1A |
zinc ion binding | ZNRF2;THRB;CPA5;CA8;ARHGEF2;TRIM10;VPS29;ZCCHC24;DDX58 |
MID2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MID2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MID2.
COX5B; ZNF24; GFI1B; ligA; CEP57L1; DYDC1; TSGA10; TMEM14B; UBE2D4; TCAF1
- Q&As
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