MKKS
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Official Full Name
McKusick-Kaufman syndrome
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Overview
This gene encodes a protein with sequence similarity to the chaperonin family. The encoded protein may have a role in protein processing in limb, cardiac and reproductive system development. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6 and McKusick-Kaufman syndrome. Two transcript variants encoding the same protein have been identified for this gene. -
Synonyms
MKKS; McKusick-Kaufman syndrome; BBS6; McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin; Bardet Biedl syndrome 6 protein; HMCS; KMS; McKusick Kaufman syndrome; McKusick Kaufman/Bardet Biedl syndromes putative chaperonin; MKS; bardet-Biedl syndrome 6 protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Rhesus Macaque
- Zebrafish
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | MKKS-726H | Recombinant Human MKKS | Mammalian Cell | His | ||
Human | MKKS-1114HCL | Recombinant Human MKKS cell lysate | N/A | |||
Human | MKKS-3478H | Recombinant Human MKKS Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Human | MKKS-5362H | Recombinant Human MKKS Protein, GST-tagged | Wheat Germ | GST | ||
Human | MKKS-6276HF | Recombinant Full Length Human MKKS Protein, GST-tagged | In Vitro Cell Free System | GST | 570 amino acids | |
Human | MKKS-3478H-B | Recombinant Human MKKS Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rhesus Macaque | MKKS-2777R | Recombinant Rhesus monkey MKKS Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | MKKS-2598R | Recombinant Rhesus Macaque MKKS Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | MKKS-2598R-B | Recombinant Rhesus Macaque MKKS Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | MKKS-10512Z | Recombinant Zebrafish MKKS | Mammalian Cell | His | ||
Chicken | MKKS-4284C | Recombinant Chicken MKKS | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- MKKS Related Articles
MKKS involved in several pathways and played different roles in them. We selected most pathways MKKS participated on our site, such as Assembly of the primary cilium, BBSome-mediated cargo-targeting to cilium, Cargo trafficking to the periciliary membrane, which may be useful for your reference. Also, other proteins which involved in the same pathway with MKKS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Assembly of the primary cilium | MARK4;DCTN1A;CCDC41;NPHP3;NDE1;CEP135;BBS1;CLUAP1;KIF3B |
BBSome-mediated cargo-targeting to cilium | CCT4;TCP1;CCT8;BBS12;BBS1;PROL1;CCT3;BBS4;SSTR3 |
Cargo trafficking to the periciliary membrane | UNC119.1;RHOL;TCP1;UNC119B;SSTR3;RAB3IP;EXOC8;ARL3;EXOC5 |
Organelle biogenesis and maintenance | IFT20;DAP3;TTC30A2;BBS13;MRPL41;CEP89;ARL3;MRPS24;TTC8 |
MKKS has several biochemical functions, for example, ATP binding, RNA polymerase II repressing transcription factor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MKKS itself. We selected most functions MKKS had, and list some proteins which have the same functions with MKKS. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | KIF6;GRK1B;MCM5;CSNK1D;PSKH1;MYH7;CAMKK1B;EPHA4A;ABCC5 |
RNA polymerase II repressing transcription factor binding | SIN3A;MTA2;PPARA;MKKS;MTA1;RBBP8;TCF7L2;BBS1;GSC |
protein binding | FUZ;LRRC29;RAB26;SIX5;CDK5RAP3;ING2;LPAR1;HSPA1L;JAKMIP2 |
unfolded protein binding | DNAJA1;HSPA1L;RUVBL2;TMEM67;HSPA1A;SERPINH1;TBCA;CCT3;RP2 |
MKKS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MKKS here. Most of them are supplied by our site. Hope this information will be useful for your research of MKKS.
BBS7; BBS10; BBS12
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