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MOCS3

Official Full Name

molybdenum cofactor synthesis 3
Overview

Molybdenum cofactor (MoCo) is necessary for the function of all molybdoenzymes. One of the enzymes required for the biosynthesis of MoCo is molybdopterin synthase (MPT synthase). The protein encoded by this gene adenylates and activates MPT synthase. This gene contains no introns. A pseudogene of this gene is present on chromosome 14.
Synonyms

MOCS3; molybdenum cofactor synthesis 3; adenylyltransferase and sulfurtransferase MOCS3; dJ914P20.3; UBA4; ubiquitin activating enzyme E1 homolog (yeast); ubiquitin like modifier activating enzyme 4; MGC9252; MOCS 3; Molybdenum cofactor synthesis protein 3; Molybdopterin synthase sulfurylase; MPT synthase sulfurylase; UBA 4; UBA4ubiquitin activating enzyme E1 homolog; OTTHUMP00000031284; ubiquitin-like modifier activating enzyme 4; UBA4, ubiquitin-activating enzyme E1 homolog;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.Coli or Yeast
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MOCS3-143H	Recombinant Human MOCS3, His-tagged	HEK293	His		Inquiry
Human	MOCS3-4259HCL	Recombinant Human MOCS3 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MOCS3-5465H	Recombinant Human MOCS3 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MOCS3-585H	Recombinant Human MOCS3 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	MOCS3-6301HF	Recombinant Full Length Human MOCS3 Protein, GST-tagged	In Vitro Cell Free System	GST	460 amino acids	Inquiry
Mouse	MOCS3-9950M	Recombinant Mouse MOCS3 Protein	Mammalian Cell	His		Inquiry
Mouse	Mocs3-3194M	Recombinant Mouse Mocs3, His-tagged	E.Coli or Yeast	His	460	Inquiry
Mouse	Mocs3-4110M	Recombinant Mouse Mocs3 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	MOCS3-5624M	Recombinant Mouse MOCS3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	MOCS3-5624M-B	Recombinant Mouse MOCS3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	MOCS3-10478Z	Recombinant Zebrafish MOCS3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
MOCS3 Related Articles

MOCS3 involved in several pathways and played different roles in them. We selected most pathways MOCS3 participated on our site, such as Sulfur relay system, which may be useful for your reference. Also, other proteins which involved in the same pathway with MOCS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Sulfur relay system	URM1;LBH;MPST;CTU2;NFS1;MOCS3;CTU1;TST;MOCS1

MOCS3 has several biochemical functions, for example, ATP binding, URM1 activating enzyme activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MOCS3 itself. We selected most functions MOCS3 had, and list some proteins which have the same functions with MOCS3. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	PANK2;CAMKVB;DCLK1A;MCM8;AK7A;STK25B;SCYL3;RIOK2;TRPV1
URM1 activating enzyme activity
metal ion binding	SMAP2;ZNF680;RASA3;NUDT15;TDO2A;CYP4A14;ZFYVE28;ATP1A3;PPARG
molybdopterin-synthase adenylyltransferase activity
molybdopterin-synthase sulfurtransferase activity
nucleotidyltransferase activity	REV3L;GMPPA;PAPSS1;GMPPAA;OASL2;TERT;GKUP;CMASA;POLR3B
protein adenylyltransferase activity	FICD;MOCS3
protein binding	TXLNB;CCDC116;PIK3CD;TBX5A;FLRT3;ORAI3;CBLL1;HMG20A;S1PR3
sulfurtransferase activity	SULT2ST1;MOCS3;TRMU
thiosulfate sulfurtransferase activity	TST;MPST;MOCS3

MOCS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MOCS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MOCS3.

XRN2

Mendel, RR; Leimkuhler, S; et al. The biosynthesis of the molybdenum cofactors. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 20:337-347(2015).

Matsumoto, T; Yano, H; et al. Syntheses and Structures of Molybdenum-Oxo Complexes Prepared by the Reactions of [Mo-2(II)(OAc)(4)] with tert-Butyl- or Bromo-Substituted Catechols. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN 88:74-83(2015).