MOGS
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Official Full Name
mannosyl-oligosaccharide glucosidase
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Overview
This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
MOGS; mannosyl-oligosaccharide glucosidase; GCS1; glucosidase I; processing A glucosidase I; processing A-glucosidase I; CDG2B;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- His|T7
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | MOGS-7916H | Recombinant Human MOGS protein, His & T7-tagged | E.coli | His/T7 | Arg60~Leu352 (Accession # Q13724) | |
Mouse | Mogs-7917M | Recombinant Mouse Mogs protein, His & T7-tagged | E.coli | His/T7 | Leu512~Tyr834 (Accession # Q80UM7) | |
Mouse | MOGS-9954M | Recombinant Mouse MOGS Protein | Mammalian Cell | His | ||
Mouse | MOGS-5627M | Recombinant Mouse MOGS Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | MOGS-5627M-B | Recombinant Mouse MOGS Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | MOGS-5046Z | Recombinant Zebrafish MOGS | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- MOGS Related Articles
MOGS involved in several pathways and played different roles in them. We selected most pathways MOGS participated on our site, such as N-Glycan biosynthesis, Metabolic pathways, Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with MOGS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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N-Glycan biosynthesis | B4GALT3;ST6GAL2;ST6GAL2A;DPM2;FUT8;MAN1A;MGAT4C;DOLK;STT3A |
Metabolic pathways | XDH;AOX4;PPAP2D;CKMA;SUCLA2;URAH;PNP6;MCCC2;NDUFS1 |
Protein processing in endoplasmic reticulum | BAK1;MOGS;DNAJC5AA;TRAF2;SSR2;DNAJA1;STT3A;BAG1;BAXA |
MOGS has several biochemical functions, for example, catalytic activity, hydrolase activity, hydrolase activity, acting on glycosyl bonds. Some of the functions are cooperated with other proteins, some of the functions could acted by MOGS itself. We selected most functions MOGS had, and list some proteins which have the same functions with MOGS. You can find most of the proteins on our site.
Function | Related Protein |
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catalytic activity | HSD17B1;OLFM4;DDAH2;PHKB;PGAM1;PNP4A;UQCRC2B;ALDOAA;LYZ2 |
hydrolase activity | SYNJ1;CAPN2B;ATP2B2;CAPN3A;CDC14A;PSMB11;OVCA2;OTUB1B;CTSM |
hydrolase activity, acting on glycosyl bonds | LCTLB;SMPDL3A;GALCA;MUTYH;MACROD1;SMPDL3B;UNGA;SMPD1;NEIL1 |
mannosyl-oligosaccharide glucosidase activity |
MOGS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MOGS here. Most of them are supplied by our site. Hope this information will be useful for your research of MOGS.
Hmga2; Ywhae; Ywhab; Hsd3b7
- Q&As
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