Mstn
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Official Full Name
myostatin
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Overview
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. -
Synonyms
MSTN; myostatin; GDF8; Growth/differentiation factor 8; GDF-8; OTTHUMP00000163498; growth differentiation factor 8;
- Recombinant Proteins
- GMP Proteins
- Protein Pre-coupled Magnetic Beads
- Cell & Tissue Lysates
- Cattle
- Chicken
- Cynomolgus Monkey
- Human
- Human/Mouse/Rat
- Mouse
- Pig
- Rat
- Rhesus Macaque
- E. coli
- E.coli
- HEK293
- HEK293F
- HEK293T
- Human Cell
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Nicotiana Benthamiana
- NS0
- Wheat Germ
- C
- His
- Fc
- GST
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- N
- hFc
- Tag Free
- Involved Pathway
- Protein Function
- Interacting Protein
- Mstn Related Articles
- Mstn Related Research Area
Mstn involved in several pathways and played different roles in them. We selected most pathways Mstn participated on our site, such as Hypertrophy Model, which may be useful for your reference. Also, other proteins which involved in the same pathway with Mstn were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Hypertrophy Model | MSTNB;DUSP14;JUND;ANKRD1;MSTN;CYR61;IFRD1;ADAM10A;MYOG |
Mstn has several biochemical functions, for example, cytokine activity, growth factor activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Mstn itself. We selected most functions Mstn had, and list some proteins which have the same functions with Mstn. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
cytokine activity | CLCF1;CCL4;IL36RN;FLT3LG;GDF10;Gm13290;IFNA6;GPR19;IL26 |
growth factor activity | FGF10A;KLK1B3;BMP7;GDF5;VHL;FGF21;FGF4;VEGFAB;Il2 |
heparin binding | FGFR4;ADAMTS3;FGFRL1;CCDC80;CCL23;COL5A1;LPA;WISP1B;FGF12 |
identical protein binding | GM5077;SORD;ERBB3;CCL3;VWF;UBQLN1;PDCD6;NPR2;TFRC |
protein binding | ITPKB;CNOT7;SMARCAD1;SCUBE3;ELF1;FLRT3;LMLN;ARHGDIG;PLAUR |
receptor binding | CHRNA10;PVRL3B;NPPC;ANXA1;POU2F1;CYTL1;ECH1;DECR2;EPHX2 |
transforming growth factor beta receptor binding | LFT1;INHBAB;USP15;GDF10B;INHBC;TGFB1A;BMP2;TGFBR3;TGFB2 |
Mstn has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Mstn here. Most of them are supplied by our site. Hope this information will be useful for your research of Mstn.
FURIN; BMP1; WFIKKN1; ACVR2B
- Q&As
- Reviews
Q&As (5)
Ask a questionMSTN inhibitors work by blocking the activity of the MSTN protein, thus promoting muscle growth and potentially reversing muscle loss.
Some potential side effects include joint stiffness, increased risk of fractures, and insulin resistance, which require close monitoring during trials.
Overexpression of MSTN can lead to muscle atrophy and decreased muscle mass.
Researchers carefully monitor the dosage and administration of MSTN protein therapy through preclinical and clinical studies to establish the optimal therapeutic dose.
Possible risks include unintended effects on other organ systems and potential complications related to excessive muscle growth.
Customer Reviews (3)
Write a reviewThe MSTN protein surpasses expectations in terms of quality and will undoubtedly fulfill my experimental requirements.
the manufacturer of MSTN provides exceptional technical support, offering valuable assistance in troubleshooting and experimental design.
The outstanding level of customer service adds extra reassurance and confidence in using the MSTN protein for my scientific investigations.
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