MYOT
-
Official Full Name
myotilin
-
Overview
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.[provided by RefSeq, Oct 2008] -
Synonyms
MYOT; myotilin; MFM3; TTID; TTOD; LGMD1; LGMD1A; 57 kDa cytoskeletal protein; myofibrillar titin-like Ig domains protein; titin immunoglobulin domain protein (myotilin);
- Cell & Tissue Lysates
- Recombinant Proteins
- Human
- Mouse
- E.coli
- HEK293
- In Vitro Cell Free System
- Wheat Germ
- GST
- His
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | MYOT-4003HCL | Recombinant Human MYOT 293 Cell Lysate | HEK293 | N/A | ||
Human | MYOT-556H | Recombinant Human MYOT protein, GST-tagged | E.coli | GST | 191-498 aa | |
Human | MYOT-2496H | Recombinant Human MYOT Protein, His-tagged | E.coli | His | ||
Human | MYOT-6616HF | Recombinant Full Length Human MYOT Protein, GST-tagged | In Vitro Cell Free System | GST | 498 amino acids | |
Human | MYOT-5856H | Recombinant Human MYOT Protein, GST-tagged | Wheat Germ | GST | ||
Mouse | Myot-1811M | Recombinant Mouse Myot Protein, His-tagged | E.coli | N-His | Arg6-Leu188 |
- Involved Pathway
- Protein Function
- Interacting Protein
- MYOT Related Articles
MYOT involved in several pathways and played different roles in them. We selected most pathways MYOT participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MYOT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|
MYOT has several biochemical functions, for example, actin binding, alpha-actinin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MYOT itself. We selected most functions MYOT had, and list some proteins which have the same functions with MYOT. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
actin binding | KLHL4;SMYHC2;GCSAM;DSTN;KLHL1;CLMN;SPIRE1A;EPS8L1;UPF3B |
alpha-actinin binding | KCNA5;PPARG;ADORA2A;KCNN2;MYOT;MAGI1;LRRC10;ALMS1;PKD2L1 |
protein binding | HRAS;GUCY2C;CPSF2;PDCD6IP;GRIN3A;IRX1;TMA16;HCLS1;LGALS8 |
structural constituent of muscle | CAPN3;SORBS2;MYL3;PDLIM3;MYBPC2;TCAP;OBSCN;ANKRD2;MYL2 |
MYOT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYOT here. Most of them are supplied by our site. Hope this information will be useful for your research of MYOT.
FLNC; NME7; AXIN1; PDLIM3; TFG; GPRASP2; DOCK9; LRP12
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All MYOT Products
Required fields are marked with *
My Review for All MYOT Products
Required fields are marked with *