NR5A1
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Official Full Name
nuclear receptor subfamily 5, group A, member 1
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Overview
The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. [provided by RefSeq, Jul 2008] -
Synonyms
NR5A1; nuclear receptor subfamily 5, group A, member 1; ELP; SF1; FTZ1; POF7; SF-1; AD4BP; FTZF1; SPGF8; SRXY3; steroidogenic factor 1; STF-1; nuclear receptor AdBP4; steroidogenic factor-1; adrenal 4 binding protein; adrenal 4-binding protein; fushi tarazu factor homolog 1; steroid hormone receptor Ad4BP; steroidogenic factor 1 nuclear receptor;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | NR5A1-31465TH | Recombinant Human NR5A1 | Wheat Germ | N/A | 461 amino acids | |
Human | NR5A1-1361H | Recombinant Human NR5A1, His-tagged | E.coli | His | 1-349aa | |
Human | NR5A1-368H | Recombinant Human NR5A1 | Mammalian Cell | His | ||
Human | NR5A1-3705HCL | Recombinant Human NR5A1 293 Cell Lysate | HEK293 | N/A | ||
Human | NR5A1-4436H | Recombinant Human NR5A1 protein, His-tagged | E.coli | His | 218-461aa | |
Human | NR5A1-6099H | Recombinant Human NR5A1 Protein, GST-tagged | Wheat Germ | GST | ||
Human | NR5A1-2435H | Recombinant Human NR5A1 protein, His&Myc-tagged | E.coli | His&Myc | 1-461aa | |
Human | NR5A1-3675H-B | Recombinant Human NR5A1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Human | NR5A1-6746HF | Recombinant Full Length Human NR5A1 Protein, GST-tagged | In Vitro Cell Free System | GST | 461 amino acids | |
Human | NR5A1-3675H | Recombinant Human NR5A1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | NR5A1-10874M | Recombinant Mouse NR5A1 Protein | Mammalian Cell | His | ||
Mouse | NR5A1-6191M-B | Recombinant Mouse NR5A1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | NR5A1-6191M | Recombinant Mouse NR5A1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | Nr5a1-2386M | Recombinant Mouse Nr5a1 protein, His-tagged | E.coli | His | 1-462aa | |
Rat | NR5A1-4073R | Recombinant Rat NR5A1 Protein | Mammalian Cell | His | ||
Rat | NR5A1-3732R | Recombinant Rat NR5A1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | NR5A1-3732R-B | Recombinant Rat NR5A1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Homo sapiens (Human) | RFL18363HF | Recombinant Full Length Human Steroidogenic Factor 1(Nr5A1) Protein, His&Myc-Tagged | E.coli expression system | His&Myc | Full Length (1-461aa) | |
Mus musculus (Mouse) | RFL34153MF | Recombinant Full Length Mouse Steroidogenic Factor 1(Nr5A1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-462aa) | |
Chicken | NR5A1-6634C | Recombinant Chicken NR5A1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- NR5A1 Related Articles
NR5A1 involved in several pathways and played different roles in them. We selected most pathways NR5A1 participated on our site, such as Developmental Biology, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR5A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Developmental Biology | PLXNC1;FGF18B;STX1B;COL6A3;BOC;MED29;EVL;FRS2B;ACVR1C |
Gene Expression | ZNF12;AIMP2;ZNF599;ZNF688;SNAPC3;ZNF45;NR1I2;CD3EAP;METTL1 |
Generic Transcription Pathway | ZNF215;ZNF615;PRDM7;SKIA;ZNF567;ZNF692;ZNF729;ZNF563;ZNF45 |
Nuclear Receptor transcription pathway | NR2F6;ESR2B;RORAA;NR2F6B;NR5A1;ESRRGA;RXRBB;NR5A1B;NR0B1 |
Nuclear Receptors | NR5A1;VDRB;NR1D2;NR2F2;NR2E1;RARGA;NR2C2;NR2F6;NR1H3 |
Ovarian Infertility Genes | ZP2;DAZL;NRIP1;NR5A1;GJA4;MSH5;SYNE2;INHA;DMC1 |
Transcriptional regulation of pluripotent stem cells | NR5A1;HIF3A;POU5F3;TDGF1;PRDM14;LIN28A;NR6A1;SALL4;FOXD3 |
Wnt Signaling Pathway NetPath | TAX1BP3;SOX1;PAX2;HIPK2;BCL9;TCF4;CRYBB2;TFAP2A;ANKRD6 |
NR5A1 has several biochemical functions, for example, DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NR5A1 itself. We selected most functions NR5A1 had, and list some proteins which have the same functions with NR5A1. You can find most of the proteins on our site.
Function | Related Protein |
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DNA binding | BHLHA15;TGIF2LY;PTGES2;VENT;SP1;EHF;HIST1H47;ZFP526;RBFOX3 |
RNA polymerase II distal enhancer sequence-specific DNA binding | SOX10;ESRRB;NONO;NFKB1;H2AFZ;CDX1;RXRB;POU4F1;SFPI1 |
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding | NR6A1;ESRRB;NR2F6B;NR4A2B;NR5A2;AHR;NR2E3;NR1I2;PPARD |
chromatin binding | NFIA;NSBP1;YBX1;Ar;SMC3;CITED2;FOSL2;JUB;PHF13 |
enzyme binding | TOP2B;PDCD2;LGALS9;TOP2A;P4HB;CLSTN2;SCARB2;STC2;AKT1 |
phospholipid binding | ESYT1;OSBPL1A;F3;SMURF1;PLA2G7;SYTL4;PACSIN1;BPIFC;Defa4 |
protein binding | MCM8;GCC1;MSH4;RAD23B;PHF7;CLUAP1;PASK;PRPSAP1;MYD88 |
steroid hormone receptor activity | NR4A1;RXRB;NR2F6B;NR4A2A;ESR2B;NR4A2;RXRBA;VDRA;ESR2A |
transcription coactivator activity | HCFC2;WNT3A;LPIN3;MED6;TAF1;TAF11;MMS19;KAT2B;HAND1 |
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | FOXF2A;PAX3;GLI1;TLE4;MITF;PTH;NKX2-5;MEF2C;GATA4 |
transcription regulatory region sequence-specific DNA binding | NFE2L1A;FOXJ1;NR5A2;PITX2;PSPC1;PER2;SOX4;NFE2L2A;NFE2L1 |
zinc ion binding | CD4;GATA2;APOBEC3D;LHX1;BMP1A;TRIM7;FBXO30;CNOT4B;UHRF2 |
NR5A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR5A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR5A1.
NCK2; NR0B1; PNRC2; 3bhs2_human_gene; FYN; NCK1; PIK3R1; CRK; GRB2; q7cfn3_yerpe; PROX1; cp11a_human_gene; star_human_gene; SMARCA5
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