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PFKFB3

  • Official Full Name

    6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

  • Overview

    6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene.
  • Synonyms

    PFKFB3; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; iPFK-2; PFK/FBPase 3; 6PF-2-K/Fru-2,6-P2ase 3; renal carcinoma antigen NY-REN-56; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; 6-p;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PFKFB3-24H Active Recombinant Human PFKFB3 protein, His-tagged E.coli His
Human PFKFB3-82913TH Recombinant Human PFKFB3, GST-tagged Insect Cell N/A
Human PFKFB3-518H Active Recombinant Human PFKFB3 Protein, His & GST-tagged Insect Cell His/GST
Human PFKFB3-82912TH Recombinant Human PFKFB3, GST-tagged Wheat Germ N/A
Human PFKFB3-215H Recombinant Human PFKFB3, GST-tagged Sf9 Insect Cell GST
Human PFKFB3-471HCL Recombinant Human PFKFB3 cell lysate Insect Cell N/A
Human PFKFB3-3284H Recombinant Human PFKFB3 protein, His-tagged E.coli His 243-520 aa
Rat PFKFB3-4392R Recombinant Rat PFKFB3 Protein Mammalian Cell His
Rat PFKFB3-4052R-B Recombinant Rat PFKFB3 Protein Pre-coupled Magnetic Beads HEK293
Rat PFKFB3-4052R Recombinant Rat PFKFB3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish PFKFB3-12572Z Recombinant Zebrafish PFKFB3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PFKFB3 Related Research Area

PFKFB3 involved in several pathways and played different roles in them. We selected most pathways PFKFB3 participated on our site, such as Fructose and mannose metabolism, HIF- signaling pathway, AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PFKFB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Fructose and mannose metabolismGMPPAB;ALDOB;GMDS;AKR1B1;KHK;TIGARA;PFKM;ALDOAB;PFKFB1
HIF- signaling pathwaySTAT3;NOX3;NOS2;PIK3R2;TCEB2;EGLN1;PLCG1;NOS3;PDK1
AMPK signaling pathwayGYS1;CAMKK1;SIRT1;PRKAG3;PFKFB4;SCD5;PIK3CD;PRKAG2;ADRa1A

PFKFB3 has several biochemical functions, for example, 6-phosphofructo-2-kinase activity, ATP binding, fructose-2,6-bisphosphate 2-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PFKFB3 itself. We selected most functions PFKFB3 had, and list some proteins which have the same functions with PFKFB3. You can find most of the proteins on our site.

Function Related Protein
6-phosphofructo-2-kinase activityPFKFB3;PFKFB2;PFKFB4L;PFKFB2A;PFKFB1;PFKFB4
ATP bindingSTK30;HSP90AA1.1;PTK7;SMYHC1;CKMA;PDK2;DDX4;RIPK1L;UBE2QL1
fructose-2,6-bisphosphate 2-phosphatase activityPFKFB1;PFKFB4;PFKFB3;C12orf5;TIGARA;PFKFB2;TIGARB

PFKFB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PFKFB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PFKFB3.

CUL2; maP3; q81sn0_bacan; q81va8_bacan; ARRB2; ARRB1

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