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RASGEF1A

Official Full Name

RasGEF domain family, member 1A
Synonyms

RASGEF1A; RasGEF domain family, member 1A; ras-GEF domain-containing family member 1A; CG4853; FLJ37817; CG4853 gene product;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
HEK293T
Mammalian cells

Tag

Flag
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RASGEF1A-2188H	Recombinant Human RASGEF1A, His-tagged	E.coli	His	132-481aa	$319 / 25ug
Human	RASGEF1A-2507HCL	Recombinant Human RASGEF1A 293 Cell Lysate	HEK293	N/A		Inquiry
Human	RASGEF1A-5596H	Recombinant Human RASGEF1A Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	RASGEF1A-2193HFL	Recombinant Full Length Human RASGEF1A Protein, C-Flag-tagged	Mammalian cells	Flag		Inquiry
Human	RASGEF1A-1858H	Recombinant Human RASGEF1A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	RASGEF1A-1858H-B	Recombinant Human RASGEF1A Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Rasgef1a-5385M	Recombinant Mouse Rasgef1a Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein
RASGEF1A Related Articles

RASGEF1A involved in several pathways and played different roles in them. We selected most pathways RASGEF1A participated on our site, such as ARMS-mediated activation, Axon guidance, Cytokine Signaling in Immune system, which may be useful for your reference. Also, other proteins which involved in the same pathway with RASGEF1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
ARMS-mediated activation	PEBP1;SPTB;DAB2IPB;FRS2B;DUSP5;SPNA2;CNKSR1;DUSP1;IL17RD
Axon guidance	SPRED2;LOC608458;RNF8;LIMK1;SLIT3;SRGAP3;LAMTOR2;AP2A2;SEMA6C
Cytokine Signaling in Immune system	SAMHD1;IFITM3;EIF4A2;NUP50;TRIM17;DUSP5;RASGRP4;IFI30;EDA
DAP12 interactions	AGO2;AGO1;RASGEF1A;PHB;IL17RD;SPTBN1;FGF20A;SPRED1;FGF8B
DAP12 signaling	CNKSR1;PEA15;PAQR3B;HBEGF;SPTA1;SPRED3;NRG4;GRAP2A;DUSP4
Developmental Biology	RHOAE;PAQR3B;EFNA2A;TCF3B;CDH4;EFNA5;CACNG2;SPTB;MYL12A
Downstream signal transduction	FGF8B;IL17RD;DUSP2;DUSP10;MOV10;PTPRA;FRS2B;PEA15;AGO3
Downstream signaling of activated FGFR1	DUSP9;PEA15;PTPRA;PEA15A;RASGEF1A;MARK3;DAB2IPB;PAQR3A;AGO2

RASGEF1A has several biochemical functions, for example, Ras guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RASGEF1A itself. We selected most functions RASGEF1A had, and list some proteins which have the same functions with RASGEF1A. You can find most of the proteins on our site.

Function	Related Protein
Ras guanyl-nucleotide exchange factor activity	SOS1;RAPGEF4;RASGEF1BB;RASGEF1A;ADRB1;RGL2;RASGRP4;RAB3A;RASGRP1

RASGEF1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RASGEF1A here. Most of them are supplied by our site. Hope this information will be useful for your research of RASGEF1A.

Kim, JH; Cheong, HS; et al. A Genome-Wide Association Study Identifies Potential Susceptibility Loci for Hirschsprung Disease. PLOS ONE 9:-(2014).

Fernandez, RM; Bleda, M; et al. Four new loci associations discovered by pathway-based and network analyses of the genome-wide variability profile of Hirschsprung's disease. ORPHANET JOURNAL OF RARE DISEASES 7:-(2012).