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REV3L

Official Full Name

REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
Overview

Protein reversionless 3-like (REV3L) also known as DNA polymerase zeta catalytic subunit (POLZ) is an enzyme that in humans is encoded by the REV3L gene.
Synonyms

REV3L; REV3-like, catalytic subunit of DNA polymerase zeta (yeast); REV3 (yeast homolog) like, catalytic subunit of DNA polymerase zeta; DNA polymerase zeta catalytic subunit; polymerase; DNA; zeta; POLZ; Catalytic subunit of DNA polymerase zeta; Polymerase DNA zeta; RAD54 like; REV3 yeast homolog like; Sez4; Yeasthomolog of Rev 3; hREV3; OTTHUMP00000017933; OTTHUMP00000017934; Rev-3, yeast, homolog-like (polymerase, DNA, zeta); REV3;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	REV3L-14091M	Recombinant Mouse REV3L Protein	Mammalian Cell	His	Inquiry
Mouse	REV3L-7535M	Recombinant Mouse REV3L Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	REV3L-7535M-B	Recombinant Mouse REV3L Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

REV3L involved in several pathways and played different roles in them. We selected most pathways REV3L participated on our site, such as Metabolic pathways, Fanconi anemia pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with REV3L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Metabolic pathways	CYP4A14;NDUFV1;PDHA1;PTDSS1A;GOT1;BDH1;DGKZ;HPDB;POLR3G
Fanconi anemia pathway	RAD51C;TELO2;RPA4;SLX1B;ZBTB32;REV1;REV3L;ERCC1;FUZ

REV3L has several biochemical functions, for example, 3-5 exonuclease activity, 4 iron, 4 sulfur cluster binding, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by REV3L itself. We selected most functions REV3L had, and list some proteins which have the same functions with REV3L. You can find most of the proteins on our site.

Function	Related Protein
3-5 exonuclease activity	APLF;REXO2;RAD9;TREX1;RAD1;RAD9A;EXOSC10;RAD9B;POLE
4 iron, 4 sulfur cluster binding	NDUFV1;NUBP1;NDUFS8A;TYW1;DPYDB;MUTYH;SDHB;POLA1;IREB2
DNA binding	HOXC8A;HIST1H2AO;TEAD3;POLN;E2F2;ZBTB39;FOXF1;RNF141;HIST1H2BD
iron-sulfur cluster binding	NDUFS1;FDX1B;NUBP1;ISCUB;CISD3;RTEL1;NFS1;EXO5;ABAT
metal ion binding	FTR82;ZSCAN5A;ACSM2;ZFP385C;ALOX8;ZHX1;GPR39;ZNF469;PPM1BA
nucleic acid binding	HNRNPH1L;CMTR1;KCNH7;DDX19;ZNF281B;RBMS2B;NABP2;PRDM9;SP3A
nucleotide binding	MAPK12A;CSNK1DA;RBFOX1;CLCN4-2;SRSF2A;CAMK1DA;BMPR1BB;UBE2IA;SMOK2B
nucleotidyltransferase activity	GMPPA;GMPPAB;MOCS3;CCDC111;CMASB;REV3L;OASL2;GDPGP1;TAMM41
transferase activity	PPIP5K2;CSNK1DB;UGT2B3;ZDHHC15B;STT3B;SGK2B;LASS5;NLK1;NDUFAF6

REV3L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with REV3L here. Most of them are supplied by our site. Hope this information will be useful for your research of REV3L.