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RHOBTB1

Official Full Name

Rho-related BTB domain containing 1
Overview

The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants.
Synonyms

RHOBTB1; Rho-related BTB domain containing 1; rho-related BTB domain-containing protein 1; KIAA0740; 3110048G13Rik; AI173445; AI573858; MGC107538; 1700008H16Rik; AV350930; MGC33059; MGC33841; OTTHUMP00000019662; OTTHUMP00000019663; Rho related BTB domain containing 1; Rho related BTB domain containing protein 1;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque

Source

HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	RHOBTB1-2355HCL	Recombinant Human RHOBTB1 293 Cell Lysate	HEK293	N/A	Inquiry
Human	RHOBTB1-2354HCL	Recombinant Human RHOBTB1 293 Cell Lysate	HEK293	N/A	Inquiry
Human	RHOBTB1-6136H	Recombinant Human RHOBTB1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	RHOBTB1-14169M	Recombinant Mouse RHOBTB1 Protein	Mammalian Cell	His	Inquiry
Mouse	Rhobtb1-5505M	Recombinant Mouse Rhobtb1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Mouse	RHOBTB1-7585M	Recombinant Mouse RHOBTB1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	RHOBTB1-7585M-B	Recombinant Mouse RHOBTB1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rhesus Macaque	RHOBTB1-3886R	Recombinant Rhesus monkey RHOBTB1 Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	RHOBTB1-3703R-B	Recombinant Rhesus Macaque RHOBTB1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rhesus Macaque	RHOBTB1-3703R	Recombinant Rhesus Macaque RHOBTB1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Chicken	RHOBTB1-4420C	Recombinant Chicken RHOBTB1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
RHOBTB1 Related Articles

RHOBTB1 involved in several pathways and played different roles in them. We selected most pathways RHOBTB1 participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHOBTB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ubiquitin mediated proteolysis	UBA6;DET1;RBX1;BRCA1;FBXO2;BIRC8;UBE2IB;PRPF19;PIAS4A

RHOBTB1 has several biochemical functions, for example, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RHOBTB1 itself. We selected most functions RHOBTB1 had, and list some proteins which have the same functions with RHOBTB1. You can find most of the proteins on our site.

Function	Related Protein
GTP binding	ADSSL1;RHEBL1;EHD1B;ARL11;ARL4A;RHOC;GNL1;RAB10;ARF4A

RHOBTB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHOBTB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RHOBTB1.

HSP90AB1; Cep152

Song, RL; Gu, JH; et al. Inhibition of osteoclast bone resorption activity through osteoprotegerin-induced damage of the sealing zone. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 34:856-862(2014).

Xu, RS; Wu, XD; et al. The tumor suppressor gene RhoBTB1 is a novel target of miR-31 in human colon cancer. INTERNATIONAL JOURNAL OF ONCOLOGY 42:676-682(2013).