RRAGB
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Official Full Name
Ras-related GTP binding B
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Overview
The mTORC1 kinase complex is a critical regulator of cell growth. Its activity is modulated by energy levels, growth factors, and amino acids via signaling through Akt, MAPK, and AMPK pathways. Recent studies found that the four related GTPases, RagA, Rag -
Synonyms
RRAGB; Ras-related GTP binding B; ras-related GTP-binding protein B; rag B; GTP-binding protein ragB; RAGB; bA465E19.1;
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- Involved Pathway
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- Interacting Protein
- RRAGB Related Articles
RRAGB involved in several pathways and played different roles in them. We selected most pathways RRAGB participated on our site, such as Cellular responses to stress, Energy dependent regulation of mTOR by LKB1-AMPK, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with RRAGB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Cellular responses to stress | UBN1;WIPI2;CDKN2A;PTGES3;HIST1H1B;MAPKAPK2B;HIF1AN;CBX8A;BAG3 |
Energy dependent regulation of mTOR by LKB1-AMPK | LAMTOR1;RRAGA;HBXIP;RRAGB;C7orf59 |
Gene Expression | ASZ1;ZNF566;CCNT2B;AARS;TPRKB;NR2F1;PIWIL4;ZNF333;HNRNPA0B |
Generic Transcription Pathway | COX6B1;COX5B;ZNF670;MED8;MED13A;ZNF688;ZNF263;ZNF124;ZNF792 |
IGF1R signaling cascade | HBXIP;EIF4B;RRAGA;C7orf59;RRAGB;IGF2B;LAMTOR1 |
IRS-mediated signalling | LAMTOR1;RRAGA;HBXIP;RRAGB;C7orf59 |
IRS-related events triggered by IGF1R | LAMTOR1;HBXIP;RRAGA;RRAGB;IGF2B;C7orf59 |
Insulin receptor signalling cascade | C7orf59;RRAGA;LAMTOR1;RRAGB;GRB10A;GRB10 |
RRAGB has several biochemical functions, for example, GTP binding, GTPase activity, guanyl ribonucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RRAGB itself. We selected most functions RRAGB had, and list some proteins which have the same functions with RRAGB. You can find most of the proteins on our site.
Function | Related Protein |
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GTP binding | DNAJC27;SEPT6;HHAT;RAB6A;THG1L;RAB14L;DRG1;SEPT10;RHOF |
GTPase activity | RRAS2;ARF1;GNA13B;RAB28;NOA1;MSTO1;MX1;RAB7A;OPA1 |
guanyl ribonucleotide binding | |
protein binding | VEGFAA;MTSS1;ZNF83;NRIP1;PRTFDC1;RAB27A;Serpina1b;SPG11;PCGF5 |
RRAGB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RRAGB here. Most of them are supplied by our site. Hope this information will be useful for your research of RRAGB.
RRAGC; RRAGD; LAMTOR1; LAMTOR3
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