Ryr2
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Official Full Name
ryanodine receptor 2, cardiac
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | RYR2-358H | Recombinant Human RYR2 | Mammalian Cell | His |
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| Human | RYR2-356H | Recombinant Human RYR2 protein (Cardiac), His-tagged | E.coli | His | Met1-Arg606 |
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| Human | RYR2-4019H-B | Recombinant Human RYR2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Human | RYR2-4019H | Recombinant Human RYR2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | RYR2-14608M | Recombinant Mouse RYR2 Protein | Mammalian Cell | His |
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| Mouse | RYR2-7862M | Recombinant Mouse RYR2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | RYR2-7862M-B | Recombinant Mouse RYR2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | RYR2-5209R | Recombinant Rat RYR2 Protein | Mammalian Cell | His |
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| Rat | RYR2-4868R | Recombinant Rat RYR2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | RYR2-4868R-B | Recombinant Rat RYR2 Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
- Ryr2 Related Articles
Ryr2 involved in several pathways and played different roles in them. We selected most pathways Ryr2 participated on our site, such as Calcium signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ryr2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium signaling pathway | AKR1C1;AVPR1A;SLC25A6;PDE1B;ORAI1;SLC8A2B;PTGER3;TACR1;P2RX8 |
| cAMP signaling pathway | GNAI3;HCAR2;ATP1A4;RAP1A;CAMK2D;PDE4A;ATP1B4;PAK1;PRKACB |
| Cardiac muscle contraction | COX7A2L;ATP1A1A.1;UQCRC2B;TPM4B;ATP1A2A;TPM2;ATP1A1;CACNA1SA;ACTC1B |
| Adrenergic signaling in cardiomyocytes | PIK3R3A;ADRB2;CACNA1D;PRKACBA;PPP1CAB;ADCY1A;Adcy4;MYL3;TPM4B |
| Circadian entrainment | ITPR1;GRIA2;CALM3;CAMK2A;NOS1;MAPK3;PLCB2;KCNJ5;MTNR1B |
| Insulin secretion | TRPM4;PRKACB;PDX1;ADCYAP1;PRKCG;CREB3L1;CCKAR;KCNMB4;FXYD2 |
| Oxytocin signaling pathway | MYLK3;MYL9;CALM2;CACNA2D1;PIK3CD;TRPM2;ELK1;PRKACA;GUCY1A3 |
| Pancreatic secretion | PRKCG;RAB3D;ATP1A4;PLA2G2D;CLCA5;PRKCA;CELA3B;ATP1A1;SLC4A4 |
| Hypertrophic cardiomyopathy (HCM) | ITGA3;MYH7;ITGB5;RYR2;ITGA8;CACNA2D1;ITGA10;CACNB3;ITGB1 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | CTNNA1;ACTB;AASS;JUP;ACTN3;ITGA2B;ATP2A2;TCF7L2;ITGA7 |
| Dilated cardiomyopathy | TNNC1;ITGB7;ITGA8;ITGB1;LMNA;DES;PRKACB;CACNB1;TGFB1 |
Ryr2 has several biochemical functions, for example, calcium channel activity, calcium ion binding, calcium-induced calcium release activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Ryr2 itself. We selected most functions Ryr2 had, and list some proteins which have the same functions with Ryr2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium channel activity | RYR1;CUL5;RYR2;TRPM4;CATSPER2;SLC24A5;CACNG2B;TRPC6A;P2RX1 |
| calcium ion binding | MMP3;CDH18;F7;S100V2;PCDH15;ANXA4;NOTCH2NL;PKD2;GRIN1 |
| calcium-induced calcium release activity | RYR3;PKD2;RYR2 |
| calcium-release channel activity | TRPV1;RASA3;JPH2;RYR1;RYR3;RYR2;JPH3 |
| calmodulin binding | MYH11;MAPKAPK2A;RGS2;CDK5RAP2;SLC9A1;TRPV1;ARPP21;MYO5A;MYLK |
| enzyme binding | TAF10;RYR2;CUTA;RAC1;KAT8;RCOR1;PARP1;MDM2;KDM4C |
| identical protein binding | G6PDX;AIRE;CNTN2;ERBB3;SERPINA1;KLHL7;SOD1;SIAH1;INHBA |
| intracellular ligand-gated calcium channel activity | TRPA1;ITPR1;AKR1C1;RYR2;ITPR3 |
| ion channel binding | ACTN2;FXYD1;AASS;CALM;SRC;CALM2;USP10;ACTN1;KCNQ1 |
| protein binding | CALD1;PDE1B;EP300;RRP7A;ZNF167;CCNB2;NUP107;LAMA1;RNF14 |
| protein kinase A catalytic subunit binding | EZR;PRKAR2A;PRKAR1A;PKIA;KCNQ1;RYR2;GSK3B;CSK;PJA2 |
| protein kinase A regulatory subunit binding | ARFGEF2;AKAP6;PRKACA;ARFGEF1;C2orf88;AKAP7;RYR2;AKAP9;EZR |
| protein self-association | L1CAM;ADAM8;CNTN2;ZFP639;VAMP2;AGA;BCL10;CCL5;CCDC88C |
| ryanodine-sensitive calcium-release channel activity | RYR1B;RYR1;RYR2;RYR3 |
| suramin binding |
Ryr2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ryr2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ryr2.
FKBP1B; MDM2; PRKACA; FKBP1A; vgrG7; q81z75_bacan; SMAD5; ALB; CFTR; AKAP6
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