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SENP7

Official Full Name

SUMO1/sentrin specific peptidase 7
Overview

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see;SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO;precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display;isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 (PubMed;18799455)).
Synonyms

SENP7; SUMO1/sentrin specific peptidase 7; SUMO1/sentrin specific protease 7; sentrin-specific protease 7; SUMO-1-specific protease 2; sentrin/SUMO-specific protease SENP7; KIAA1707; MGC157730;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rat

Source

E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
N/A
N
No tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SENP7-7915H	Recombinant Human SENP7	E.coli	N/A		Inquiry
Human	SENP7-405H	Recombinant Human SENP7 Protein, His-tagged	E.coli	His		Inquiry
Human	SENP7-1972HCL	Recombinant Human SENP7 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SENP7-1971HCL	Recombinant Human SENP7 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SENP7-0883H	Recombinant Human SENP7 Protein (T640-P984), Tag Free	E.coli	No tag	T640-P984	Inquiry
Human	SENP7-6065H	Recombinant Human SENP7 Protein (Met695-Ala864), N-His tagged	E.coli	N-His	Met695-Ala864	Inquiry
Human	SENP7-0884H	Recombinant Human SENP7 Protein (T640-P984), GST tagged	E.coli	GST	T640-P984	Inquiry
Rat	SENP7-5318R	Recombinant Rat SENP7 Protein	Mammalian Cell	His		Inquiry
Rat	SENP7-4977R	Recombinant Rat SENP7 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SENP7-4977R-B	Recombinant Rat SENP7 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
SENP7 Related Articles

SENP7 involved in several pathways and played different roles in them. We selected most pathways SENP7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SENP7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

SENP7 has several biochemical functions, for example, cysteine-type peptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SENP7 itself. We selected most functions SENP7 had, and list some proteins which have the same functions with SENP7. You can find most of the proteins on our site.

Function	Related Protein
cysteine-type peptidase activity	CAPN2B;CTSJ;USP43;CASP8;OTUD4;Ctsl;CASPC;CAPN3;CASPBL
protein binding	MYH7B;PPP2CB;KCND3;MCM3;GNB3;GNAI3;NPY2R;ZNF593;AGRN

SENP7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SENP7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SENP7.

CBX5; TRIM28; BCL6

Romeo, K; Louault, Y; et al. The SENP7 SUMO-Protease Presents a Module of Two HP1 Interaction Motifs that Locks HP1 Protein at Pericentric Heterochromatin. CELL REPORTS 10:771-782(2015).

Alegre, KO; Reverter, D; et al. Structural insights into the SENP6 Loop1 structure in complex with SUMO2. PROTEIN SCIENCE 23:433-441(2014).