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TRAPPC10

Official Full Name

trafficking protein particle complex 10
Overview

The protein encoded by this gene is a transmembrane protein found in the cis-Golgi complex. The encoded protein is part of the multisubunit transport protein particle (TRAPP) complex and may be involved in vesicular transport from the endoplasmic reticulum to the Golgi. Mutations in this gene could be responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy, or for autoimmune polyglandular disease type 1.
Synonyms

TRAPPC10; trafficking protein particle complex 10; TMEM1, transmembrane protein 1; trafficking protein particle complex subunit 10; EHOC 1; trafficking protein particle complex subunit 130; TRAPP 130 kDa subunit; TRS130; TRS30; EHOC1; Epilepsy holoprosencephaly candidate 1 protein; FLJ54223; FLJ54817; FLJ55683; GT 334; GT334; GT334 protein; MGC126777; Protein GT334; TMEM 1; TMEM1; Trafficking protein particle complex subunit TMEM1; Transmembrane protein 1; Transport protein particle subunit TMEM1; TRAPP subunit TMEM1; OTTHUMP00000109489; epilepsy holoprosencephaly candida; EHOC-1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
His|T7
Myc
DDK
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TRAPPC10-8075H	Recombinant Human TRAPPC10 protein, His & T7-tagged	E.coli	His/T7	Pro74~Trp357 (Accession # P48553)	Inquiry
Human	TRAPPC10-1788HCL	Recombinant Human TRAPPC10 cell lysate		N/A		Inquiry
Human	TRAPPC10-2628H	Recombinant Human TRAPPC10 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	TRAPPC10-301217H	Recombinant Human TRAPPC10 protein, GST-tagged	E.coli	GST	Ile127-Leu303	Inquiry
Human	TRAPPC10-3096H	Recombinant Human TRAPPC10 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	Trappc10-8076M	Recombinant Mouse Trappc10 protein, His & T7-tagged	E.coli	His/T7	Gly1077~Thr1259 (Accession # Q3TLI0)	Inquiry
Rhesus Macaque	TRAPPC10-4942R	Recombinant Rhesus monkey TRAPPC10 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	TRAPPC10-4756R-B	Recombinant Rhesus Macaque TRAPPC10 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	TRAPPC10-4756R	Recombinant Rhesus Macaque TRAPPC10 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein

TRAPPC10 involved in several pathways and played different roles in them. We selected most pathways TRAPPC10 participated on our site, such as Asparagine N-linked glycosylation, COPII (Coat Protein 2) Mediated Vesicle Transport, ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRAPPC10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Asparagine N-linked glycosylation	TMED10;LMAN2L;ST6GAL2B;TRAPPC2L;TRAPPC6BL;BET1;CNIH;TRAPPC1;ALG14
COPII (Coat Protein 2) Mediated Vesicle Transport	TRAPPC2;PPP6R3;TRAPPC3;CTSC;TRAPPC9;AREG;ANKRD28;NAPG;GORASP1
ER to Golgi Anterograde Transport	NAPG;NSFB;AREG;NSFA;TRAPPC2;SEC23IP;ANKRD28;SCFD1;TMED2
Membrane Trafficking	TFR1B;TGOLN2;ANKRD28;PPP6C;PLDN;DTNBP1;STAM2;GORASP1;YKT6
Metabolism of proteins	GALNTL5;FURINB;GALNT5;TBCB;DPH3;TRAPPC5;SPCS3;TRAPPC6B;BCS1L
Post-translational protein modification	PHC1;SLC35A1;ADAMTS13;TMED10;SEC23IP;DOHH;ADAMTS20;NAPAB;YKT6
Transport to the Golgi and subsequent modification	ANKRD28;SEC22C;PPP6R3;TRAPPC6B;TRAPPC1;MGAT4A;SCFD1;TMED10;NAPG
Vesicle-mediated transport	MYO6A;CLVS1;GJA4;CLINT1;FTH1A;GJD3;NFX1;SCFD1;GJB3

TRAPPC10 has several biochemical functions, for example, protein binding, sodium ion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRAPPC10 itself. We selected most functions TRAPPC10 had, and list some proteins which have the same functions with TRAPPC10. You can find most of the proteins on our site.

Function	Related Protein
protein binding	RNF115;SLC30A2;NDFIP1;MUC7;TFDP1;LAMP2;MSN;MYO6;GRHL3
sodium ion transmembrane transporter activity	SLC23A1;SLC12A10.3;TRAPPC10;ASIC4;SLC12A10.2;SLC12A3;SLC12A10.1;SLC12A1;CNNM4

TRAPPC10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRAPPC10 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRAPPC10.

RAB3IP; AMOTL2