TRIO
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Official Full Name
TrioB6
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Overview
Triple functional domain protein is a protein that in humans is encoded by the TRIO gene. TRIO (gene) has been shown to interact with Filamin and RHOA. -
Synonyms
trio;0368/10;0959/14;1372/03;1386/06;BEST:LD36950;CG18214;CG9208;Dmel\CG18214;DTrio;l(3)036810;l(3)6D104;l(3)S036810;l(3)S095914;l(3)S137203;l(3)S138606;l(3)S[1372/3];l(3)S[1386/06];l(3)trio;M89;UNC-73/Trio;CG18214 gene product from transcript CG18214-RA;CG18214-PA;CG18214-PB;CG18214-PC;CG18214-PD;CG18214-PE;CG18214-PF;trio-PA;trio-PB;trio-PC;trio-PD;trio-PE;trio-PF;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Mouse | TRIO-17404M | Recombinant Mouse TRIO Protein | Mammalian Cell | His |
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| Mouse | TRIO-9628M-B | Recombinant Mouse TRIO Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | TRIO-9628M | Recombinant Mouse TRIO Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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- Involved Pathway
- Protein Function
- Interacting Protein
- TRIO Related Articles
TRIO involved in several pathways and played different roles in them. We selected most pathways TRIO participated on our site, such as Axon guidance, Cell death signalling via NRAGE, NRIF and NADE, DCC mediated attractive signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | MYL12B;EFNB3;DNM2;PPP3CC;RGMA;PEA15;SLIT2;PLXND1;DUSP4 |
| Cell death signalling via NRAGE, NRIF and NADE | AKAP13;MCF2L;ITGB3BP;FGD2;ARHGEF18A;ARHGEF18;ARHGEF3;FGD4;ARHGAP4A |
| DCC mediated attractive signaling | TRIO;NTN1A;DCC;DOCK1;NTN1B |
| Developmental Biology | BOC;ITSN1;SIAH2;ARPC1B;KLB;MED18;NRP2;MED22;DNM1 |
| G alpha (12/13) signalling events | KALRNB;ARHGEF9;ADRA1D;ARHGAP4A;FGD2;FGD4;OBSCN;KALRN;ARHGEF3 |
| G alpha (q) signalling events | ARHGEF25;TAC2;RASGRP2;TRPC6A;KALRNB;NMBA;ABHD6B;TRPC7;UTS2D |
| GPCR downstream signaling | OPN4;VIP2;RGS12;PTH2;CNR2;TAC1;ADORA2B;ADM2;ITSN1 |
| Gastrin-CREB signalling pathway via PKC and MAPK | ANXA1A;CCK;TRPC7;OPN4.1;PROKR1A;GPR65;PMCH;DGKQ;MGLL |
TRIO has several biochemical functions, for example, ATP binding, Rho guanyl-nucleotide exchange factor activity, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIO itself. We selected most functions TRIO had, and list some proteins which have the same functions with TRIO. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | VRK2;HIPK4;SMC1AL;CCT6B;ACACA;PIM2;TOP2B;PSTK;DDX5 |
| Rho guanyl-nucleotide exchange factor activity | FGD6;C3A.1;KALRN;ARHGEF11;PLEKHG2;FGD3;FGD4A;ARHGEF1B;DOCK11 |
| enzyme binding | TTN;APBA3;A2M;RAC1;CABYR;XRCC1;ZFHX3;PRKCH;CYP1A2 |
| guanyl-nucleotide exchange factor activity | RANGRF;ARHGEF19;FLCN;RASGRP1;SERGEF;PREX1;ITSN2A;ARHGEF17;TBXAS1 |
| kinase activity | PTK6B;PAK2A;HYKK.2;CSNK2A2A;PKN2;TSSK1;SGK2A;MAP4K6;TLK1B |
| nucleotide binding | MSI2;HELZ;GNAI2B;NTRK2B;SFPQ;EIF2S3Y;GRK7A;PFKMB;EEF2A.1 |
| protein kinase activity | TLK1B;CSNK1G3;CLK4B;MAP4K5;BRAF;PRKCA;STK35L;MAPKAPK2A;PAK1 |
| protein serine/threonine kinase activity | NEK6;PIM3;BMPR1AA;PRPF4B;DSTYK;MAPK8A;CAMK1GA;LATS1;RPS6KAL |
| transferase activity | ZDHHC22;GOT2B;BMPR2A;TRMT10C;GLT8D1;GCNT4A;PKMB;GALNT11;HS2ST1A |
TRIO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIO here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIO.
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