VASP
-
Official Full Name
VASP vasodilator-stimulated phosphoprotein
-
Overview
VASP (vasodilator stimulated phosphoprotein) plays an important role in ANF/NO/cGMP Protein kinase and cAMP/cAMP Protein kinase signalling pathways. VASP is expressed in almost all human and animal cell lines; particularly high concentrations are found in thrombocytes, vascular smooth muscle cells and fibroblasts. In cultured cells VASP is associated with focal contacts, cell-cell-contacts, microfilaments and dynamic membrane regions such as the leading edge. In vitro binding data show that VASP binds to profilin, zyxin, vinculin, and the Listeria spp. surface protein ActA. Functional evidence indicates that VASP is a crucial factor involved in the enhancement of actin filament formation. -
Synonyms
VASP; vasodilator-stimulated phosphoprotein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Flag
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | VASP-3500H | Recombinant Human VASP, His-tagged | E.coli | His | ||
Human | VASP-30994TH | Recombinant Human VASP, His-tagged | E.coli | His | 343 amino acids | |
Human | VASP-426HCL | Recombinant Human VASP 293 Cell Lysate | HEK293 | N/A | ||
Human | VASP-1570H | Recombinant Human VASP Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | VASP-1409HFL | Recombinant Full Length Human VASP Protein, C-Flag-tagged | Mammalian cells | Flag | ||
Human | VASP-2332H-B | Recombinant Human VASP Protein Pre-coupled Magnetic Beads | HEK293 | |||
Human | VASP-2332H | Recombinant Human VASP Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | VASP-17986M | Recombinant Mouse VASP Protein | Mammalian Cell | His | ||
Mouse | VASP-9999M-B | Recombinant Mouse VASP Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Vasp-6901M | Recombinant Mouse Vasp Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | VASP-9999M | Recombinant Mouse VASP Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
- Involved Pathway
- Protein Function
- Interacting Protein
- VASP Related Research Area
VASP involved in several pathways and played different roles in them. We selected most pathways VASP participated on our site, such as Rap signaling pathway, cGMP-PKG signaling pathway, Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with VASP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Rap signaling pathway | FGF20;PLCB3;CALML3;INS;AKT2;MAP2K3;ANGPT4;MAPK3;CALML5 |
cGMP-PKG signaling pathway | PLCB4;PDE3A;KCNMB4;IRS1;PLN;GNA12;INS1;MAP2K1;NFATC3 |
Focal adhesion | PIK3R5;ITGA7;PDPK1B;FYNB;MYLK4;LAMA4;MAPK9;ITGB8;PDGFAA |
Platelet activation | ROCK1;PRKACG;P2RY12;GP9;GP5;MYLK3;NOS3;AKT2;MYLK2 |
Fc gamma R-mediated phagocytosis | PAK1;ARF6;RAC1;WASF3;LAT;WAS;GAB2;SPHK2;PLA2G6 |
Leukocyte transendothelial migration | ROCK1;PIK3CG;VAV1;GNAI3;PXN;CLDN4;CDC42;ACTN3;CLDN10 |
VASP has several biochemical functions, for example, SH3 domain binding, actin binding, profilin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VASP itself. We selected most functions VASP had, and list some proteins which have the same functions with VASP. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
SH3 domain binding | SH3BP5L;PTPN12;INPP5J;ZFP106;EVL;ARHGAP17;SHANK2;REPS1;PLSCR4 |
actin binding | DAAM1;SHROOM1;MYO1G;SPATA32;MYH9;GSNA;MYBPC2;GCSAM;XIRP2 |
profilin binding | EVL;FMNL1;DIAP1;DIAPH1;WIPF1;CTTN;RHOQ;HTT;CYFIP1 |
protein binding | IRF5;UNC45A;PPP1R3C;TGM1;STK3;RPL11;RINL;RBM15B;ZNF187 |
VASP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VASP here. Most of them are supplied by our site. Hope this information will be useful for your research of VASP.
XIRP1; BAIAP2; FGFR1OP; SCGB2A2; ABI2
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All VASP Products
Required fields are marked with *
My Review for All VASP Products
Required fields are marked with *