Creative BioMart to Present at IMMUNOLOGY2024™|May 3-7, 2024|Booth #512 Learn More

ZHX3

Official Full Name

zinc fingers and homeoboxes 3
Overview

This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor.
Synonyms

ZHX3; zinc fingers and homeoboxes 3; TIX1, triple homeobox 1; zinc fingers and homeoboxes protein 3; KIAA0395; triple homeobox 1; triple homeobox protein 1; zinc finger and homeodomain protein 3; TIX1;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ZHX3-1983HCL	Recombinant Human ZHX3 cell lysate		N/A		Inquiry
Human	ZHX3-3721H	Recombinant Human ZHX3 protein, GST-tagged	E.coli	GST	848-956 aa	$319 / 25ug
Mouse	Zhx3-7108M	Recombinant Mouse Zhx3 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rat	ZHX3-6707R	Recombinant Rat ZHX3 Protein	Mammalian Cell	His		Inquiry
Rat	ZHX3-6339R	Recombinant Rat ZHX3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	ZHX3-6339R-B	Recombinant Rat ZHX3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	ZHX3-5293R	Recombinant Rhesus monkey ZHX3 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	ZHX3-5106R	Recombinant Rhesus Macaque ZHX3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	ZHX3-5106R-B	Recombinant Rhesus Macaque ZHX3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	ZHX3-9847Z	Recombinant Zebrafish ZHX3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ZHX3 Related Articles

ZHX3 involved in several pathways and played different roles in them. We selected most pathways ZHX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZHX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

ZHX3 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZHX3 itself. We selected most functions ZHX3 had, and list some proteins which have the same functions with ZHX3. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	MLLT10;IKZF1;ZNF615;RX2;ZNF8;SETDB1A;HIST1H4H;ZFP689;NFE2L2B
metal ion binding	GNE;ZBTB2;NT5C2L1;POLR3B;BMPR1BB;TKTL2;TKTL1;CSGALNACT1;MYSM1
protein binding	TYK2;PPP1R12A;CACNB4;FAM96A;SLC30A8;TTC39B;EVI5L;GJA1;GPBP1
protein heterodimerization activity	BOK;AOC3;UBA3;BCL11A;CUL5;INHBA;CABYR;ENO2;TENM3
protein homodimerization activity	BCL2L1;SEPHS1;P2RX7;TBX15;THRA;ERP29;APOA4;BMP4;DMRT2A
transcription corepressor activity	NSD1;TBL1Y;KCTD1;ZFPM1;TLE4;GPS2;CCAR1;NR0B2;CREG1
transcription factor activity, sequence-specific DNA binding	NR1D2A;KDM5A;GTF3A;ZFP1;JUNBB;ZHX1;HMGA1;ZBTB14;ZNF134

ZHX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZHX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZHX3.

NLK; ATXN1; q8ckl9_yerpe; q9wmx2-pro_0000037548; mdm2_human_probe

Lee, JH; Nam, H; et al. Upregulation of GM-CSF by TGF-beta 1 in epithelial mesenchymal transition of human HERS/ERM cells. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 50:399-405(2014).

Chaudhry, P; Fabi, F; et al. Prostate apoptosis response-4 mediates TGF-beta-induced epithelial-to-mesenchymal transition. CELL DEATH & DISEASE 5:-(2014).