The neurotrophin-3 and p75NTR symmetrical
Cat.No. : | CBCRY18 |
- Specification
- Gene Information
- Related Products
Cat. No. : | CBCRY18 |
Background : | Neurotrophins (NTs) are important regulators for the survival, differentiation and maintenance of different peripheral and central neurons. NTs bind to two distinct classes of glycosylated receptor: the p75 neurotrophin receptor (p75(NTR)) and tyrosine kinase receptors (Trks). Whereas p75(NTR) binds to all NTs, the Trk subtypes are specific for each NT. |
Protein Classification : | signaling protein |
Structure Weight : | 63861.22 |
Polymer : | 1 |
Molecule : | Neurotrophin-3 |
Chain Length : | 119 amino acids |
PDB ID : | 3BUK |
MMDB ID : | 65479 |
Source : | E.coli |
Method : | X-Ray Diffraction |
Resolution : | 2.6Å |
Ligand Chemical Component : | N-Acetyl-D-Glucosamine |
Reference : | Gong, Y., Cao, P., Yu, H.J., Jiang, T.(2008) Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex.Nature454: 789-793 |
Gene Name : | NTF3 |
Synonyms : | HDNF; MGC129711; NGF-2; NGF2; NT3; Nerve growth factor 2; neurotrophic factor; neurotrophin 3 |
UniProt ID : | P20783 |
Chromosome Location : | 12p13 |
Function : | growth factor activity; nerve growth factor binding; neurotrophin receptor binding |
Gene ID : | 4804 |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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