Recombinant Human ADRB2 protein
Cat.No. : | ADRB2-25H |
Product Overview : | Recombinant Human ADRB2 was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. |
Source : | Wheat Germ |
Species : | Human |
Form : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
Molecular Mass : | 46.6 kDa |
AA Sequence : | MGQPGNGSAFLLAPNRSHAPDHDVT QQRDEVWVVGMGIVMSLIVLAIVFG NVLVITAIAKFERLQTVTNYFITSL ACADLVMGLAVVPFGAAHILMKMWT FGNFWCEFWTSIDVLCVTASIETLC VIAVDRYFAITSPFKYQSLLTKNKA RVIILMVWIVSGLTSFLPIQMHWYR ATHQEAINCYANETCCDFFTNQAYA IASSIVSFYVPLVIMVFVYSRVFQE AKRQLQKIDKSEGRFHVQNLSQVEQ DGRTGHGLRRSSKFCLKEHKALKTL GIIMGTFTLCWLPFFIVNIVHVIQD NLIRKEVYILLNWIGYVNSGFNPLI YCRSPDFRIAFQELLCLRRSSLKAY GNGYSSNGNTGEQSGYHVEQEKENK LLCEDLPGTEDFVGHQGTVPSDNID SQGRNCSTNDSLL |
Applications : | Antibody Production; Functional Study; Compound Screening |
Notes : | Heating may cause protein aggregation. Please do not heat this product before electrophoresis. Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | ADRB2 adrenoceptor beta 2 [ Homo sapiens ] |
Official Symbol : | ADRB2 |
Synonyms : | BAR; B2AR; ADRBR; ADRB2R; BETA2AR; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2 surface; beta-2 adrenoceptor; beta-2 adrenoreceptor; catecholamine receptor |
Gene ID : | 154 |
mRNA Refseq : | NM_000024 |
Protein Refseq : | NP_000015 |
MIM : | 109690 |
UniProt ID : | P07550 |
Chromosome Location : | 5q32 |
Pathway : | Adrenergic signaling in cardiomyocytes, organism-specific biosystem; Arf6 signaling events, organism-specific biosystem; Endocytosis, organism-specific biosystem |
Function : | adenylate cyclase binding; epinephrine binding; protein binding |
Products Types
◆ Recombinant Protein | ||
ADRB2-30C | Recombinant Cynomolgus Monkey ADRB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADRB2-88R | Recombinant Rhesus Macaque ADRB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Adrb2-88M | Recombinant Mouse Adrb2 Protein, GST-tagged | +Inquiry |
Adrb2-89R | Recombinant Rat Adrb2 Protein, His-tagged | +Inquiry |
ADRB2-366M | Recombinant Mouse ADRB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ADRB2-34HCL | Recombinant Human ADRB2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2187 | cAMP ADRB2 (B2AR) CHO-K1 GPCR Assay Kit | +Inquiry |
Kit-2185 | ADRB2 Total GPCR Internalization Assay Kit | +Inquiry |
Kit-2186 | ADRB2 CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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