Recombinant Human PDX1 Protein, His-tagged
Cat.No. : | PDX1-393H |
Product Overview : | Recombinant Human PDX1 fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell. |
Source : | E. coli |
Tag : | His |
Form : | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Molecular Mass : | 30.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | PDX1 pancreatic and duodenal homeobox 1 [ Homo sapiens ] |
Official Symbol : | PDX1 |
Synonyms : | PDX1; pancreatic and duodenal homeobox 1; insulin promoter factor 1, homeodomain transcription factor , IPF1; pancreas/duodenum homeobox protein 1; IDX 1; MODY4; PDX 1; somatostatin transcription factor 1; STF 1; IPF-1; IUF-1; glucose-sensitive factor; insulin upstream factor 1; islet/duodenum homeobox-1; pancreatic-duodenal homeobox factor 1; somatostatin-transactivating factor 1; insulin promoter factor 1, homeodomain transcription factor; GSF; IPF1; IUF1; IDX-1; PDX-1; STF-1; |
Gene ID : | 3651 |
mRNA Refseq : | NM_000209 |
Protein Refseq : | NP_000200 |
MIM : | 600733 |
UniProt ID : | P52945 |
Products Types
◆ Recombinant Protein | ||
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Pdx1-2749R | Recombinant Rat Pdx1 Protein, His&GST-tagged | +Inquiry |
PDX1-1642H | Recombinant Human PDX1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Pdx1-4780M | Recombinant Mouse Pdx1 Protein, Myc/DDK-tagged | +Inquiry |
PDX1-4022R | Recombinant Rat PDX1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PDX1-3318HCL | Recombinant Human PDX1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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