Recombinant Mouse Il2 protein, His-tagged
Cat.No. : | Il2-553M |
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Product overview : | Recombinant Mouse Il2 (P04351) aa. (Ala21~Gln169) fused with His tag was produced in HEK293F cells. |
Source : | HEK293F |
Species : | Mouse |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 18.9kDa; Accurate Molecular Mass: 25kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Ala21~Gln169 |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >98% |
Characteristic : | Isoelectric point is 4.9. |
Applications : | Cell culture; Activity Assays; In vivo assays. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | 20mM Tris, 150mM NaCl,pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex |
Gene Name : | Il2 interleukin 2 [ Mus musculus (house mouse) ] |
Official Symbol : | Il2 |
Synonyms : | Il2; interleukin 2; Il-2; interleukin-2; T-cell growth factor; TCGF |
Gene ID : | 16183 |
mRNA Refseq : | NM_008366.3 |
Protein Refseq : | NP_032392.1 |
UniProt ID : | P04351 |
Products Types
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionIL2 promotes the formation of memory T-cells.
IL2 has a pro-tumorigenic role in the tumor microenvironment.
IL2 synergizes with IL-12 in a mixed cytokine environment.
IL2 upregulates the expression of PD-1 checkpoint inhibitors.
IL2 is rapidly internalized by activated T-cells.
IL2 induces M1 macrophage polarization.
IL2 increases blood-brain barrier permeability.
IL2's affinity for its receptor decreases under hypoxic conditions.
IL2's bioactivity is enhanced by glycosylation.
IL2 promotes the differentiation of Th17 cells.
Customer Reviews (3)
Write a reviewPotent in T-cell activation.
Suitable for cytokine assays.
High stability.
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