Biotech Industry News And Bioscience News
Stat5 Protein is an Important Target for the Research of Prostate Cancer
Among many factors that affect prostate cancer, Stat5 is one of the important. As early as in 2003, scientists have discovered that Stat5 protein is critical for viability of prostate cancer cells and growth of prostate tumors in mice. In 2005, researchers demonstrated that Stat5 activity was
Protein Localization: Compare the Microscopy-based and Fluorescent Protein Tagging Method
The picture shows the experimentally-determined subcellular localization of almost 500 human proteins using both immunofluorescence and GFP-tagging. Microscopy-based method and fluorescent protein tagging method are two of the most widely used approaches to determine protein localization.
Scientists Found the Key Protein of P. Aeruginosa Infecting Humans
Pseudomonas aeruginosa, an environmental pathogen, usually exists in soil, water and other environment outside of the body. However, it causes common hospital acquired infection. According to yesterday’s mBio report, scientists have discovered the previously unknown virulence factor in
Researchers Discovered the Energy and Pathway of Opening and Closing of Ion Channel
Ion channels are pore-forming membrane proteins. They are important components in many biological processes that involve rapid changes in cells, for example, cardiac, skeletal, and smooth muscle contraction, epithelial transport of nutrients and ions, T-cell activation and pancreatic
PNAS: Scientists Unveiled a Novel Feature of DEAD-box Proteins
As reported on the Early Edition of the Proceeding of the National Academy of Science on Apr. 29, 2013, scientists have uncovered how DEAD-box proteins and its cofactors can specifically work on other proteins with nonspecific biochemical activity. DEAD-box proteins are a large class of
Structural Finding for Us to Better Understand the Role of MITF
Microphthalmia associated transcription factor (MITF) works as a master regulator in cells which produce melanocytes. It is crucial for the development, survival and differentiation of melanocytes. It also plays important roles in other cell type. This time, scientists resolved the structure
Using New Custom Antibodies Banish Microbes
Many bacteria have developed resistance to current antibiotics, even super-bugs are raging. Old bacteria mutate to adopt antibiotics. In order to solve this problem, some researchers caught an idea that they planned to use antibodies to trigger the body response. We know antibodies will be
The Role of Protein SFRP2 on Human Cancers and New Clue for Drug Development
When researchers tried to find an alternative to the anti-tumor drug—Avastin (bevacizumab) that target on VEGF to inhibit angiogenesis, they found more roles of SFRP2, especially as a stimulator of angiogenesis. Protein SFRP2, secreted frizzed-related protein 2, according to the
Researchers Developed New Antibiotic for Broad-range and “Resistance-free”
The scanning electron micrograph shows macrophages infected with Bacillus anthracis Viruses using phage attack bacteria. With billions of years’ experience, phages have trained their
Should Genes Be Patented?
With the development and increasingly use of genetic technologies, genes are drawing numerous attention from various perspectives, such as for basic research, clinical application, applied science, agriculture, industry, chemistry, biology and so on. In life science, genes are found to be
Scientists Innovatively Modified an Approach to Dissect Kinases
The top is a structural model of uniRapR domain which binds small molecule rapamycin. The bottom left depicts inactive state of the protein of interest modified with uniRapR domain. Binding of rapamycin and uniRapR reactivates the protein (bottom right). The approach mentioned here is
Nature Genetics: the Mapping of Telomerase was Disclosed for the First Time
Telomerase is an important enzyme that adds DNA sequence repeats to the 3’ end of DNA strands in the telomere region. It is one of the fundamental enzymes in cell biology. It is a reverse transcriptase and shortened after every replication cycle. In 1970s, scientists have assumed that
PNAS: Scientists Developed New Approach to Resolve Protein Structure
Recently scientists developed a new strategy that can be used to study protein structures that can’t be realized previously. The new strategy combined computational modeling and experimental physicochemical techniques. The results were published on the journal of Proceedings of the
Nature: the New Immunity Pathway was Confirmed
Our immune system is a natural defense that keeps harmful things out in normal conditions. But of course, this defense won’t always work. Overall, our immune system works by differentiating normal things from abnormal things, such as between cells and microbes. While in terms of
Scientists Unveiled the Mysterious Procedure in Human DNA Replication
As an illustration, the picture represents a crucial molecular player in the process, by a hand, which is loading the sliding clamp ring onto DNA. According to the report of eLife on April 2, 2013, the long mysterious mechanism in human DNA replication has been identified for the first
Scientists Found Novel Monoclonal Antibody for CLL
Chronic lymphocytic leukemia (CLL) is one kind of blood cancer. It is the second most common type of leukemia in adults. It is also the most common type of blood cancer in America. According to authentic statistics, it is estimated that 16,060 men and women will be diagnosed with and 4,580 men
PNAS: A New Study Revealed the Spread Path of Cell Transmission
Microscope image of Nerve cells: Spreading of protein particles between cells. According to a newly published lab study in the Proceedings of the National Academy of Sciences (PNAS), some protein particles can multiply and spread cell transmission. This finding would be meaningful for
Induce Some Cells into other Cells without via Stem Cells
Reprogramme skin and glia cells into nerve cells Re-programmed nerve cell When I mentioned about turning one cell type into other cell type, will you think
Researchers Developed a Model That Explains How Nucleosomes Recognize Protein
The pictures shows the model how proteins move along DNA Most of the DNA in evolved organisms is wrapped around proteins, forming the basic unit of DNA packaging, nucleosomes as the picture shows. But how exactly these nucleosomes are recognized and read by protein is unclear. In order to find
The Company Acquire of Life Technologies Corp
The auction of Life Technologies Corp, which is a genetic testing company, has been attracting more “visitors” with exception for previous KKR & Co LP, Hellman & Friedman LLC, Thermo Fisher Scientific Inc, Danaher Corp and a buyout consortium of Blackstone Group LP, private
Scientific Report: Testing DNA Methylation with Novel Assay
According to the Scientific Report, researchers have developed a new, single molecule test for detecting methylated DNA. DNA Methylation is a biochemical process that involves the addition of a methyl group to the cytosine or adenine DNA nucleotides. Through this way, it regulates gene
New Clue Was Found Regarding the New Coronavirus: Protein DPP4
Keep tracing on the news we released several days ago about the coronavirus in Europe, we found progression in accordance with the Nature report on Mar. 14.
Cell: The Role of EDRA Gene in Evolution
The picture shows the mice carrying a human version of the EDAR gene have footpads with more sweat glands (blue tubes). About 30,000 years ago, China was a warm and humid place. Thus people living here usually have more sweat glands to cool self temperature. But why and how is unclear to
2nd Monoclonal Antibodies Summit & Trade Exhibition
Creative BioMart is very pleased to introduce the conference to mutually promote advances in diagnostic & therapeutic antibody development.
Besides Cell Lines Culture, Lipid Storage etc., a New Application of Gene Plin2 was Found
Nowadays weight losing is very popular among women, even men. They adopt diet, exercise, medicine control etc. to achieve the result. But every coin has two sides and you need to pay something. On Lipid Research, a two-year study revealed an exciting finding that deleting a specific gene in mice
