Biotech Industry News And Bioscience News
The Therapeutic Applications of Recombinant Interferons
Interferons are members of cytokines. They get the name after their ability to “interfere” with viral replication within host cells. They play vital functions in activating immune cells, recognition of infection or tumor cells, strengthening the ability of uninfected hot cells to resist
A Reliable Recombinant Proteins Supplier
The application of recombinant proteins: To identify the polypeptide coded by a DNA-sequence To analyze the biological activity To study the structure-function relationships, interactions To study the 3D-structure To do protein engineering and design To raise specific antibodies To develop a
Industry Analysis: The Application and Development Trend of Recombinant Proteins
Recombinant proteins are manufactured by genetic engineering, cell engineering or other technologies, derived from organisms. Recombinant proteins have become one of the most products for current biology industry. From a broad range, recombinant proteins include recombinant proteins of
Two VEGF-related Studies and the Findings
Vascular endothelial growth factor, or VEGF, is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. VEGF signals through the three receptors: fms-like tyrosine kinase, KDR and the flt4. It
Scientists Uncover the Crystal Structures of Class B GPCRs and Expand Their Pharmaceutical Importance
GPCRs, a kind of membrane receptors, serve as extracellular signal sensors, including photons, ions, small organic molecules, even the whole proteins. About one third of known drugs use GPCRs to be active targets. Currently, all the published GPCR structures come from class A. But recently the
Epidermal Growth Factor Receptor and Its Applications
The discovery of growth factors won the Nobel Prize in Medicine in 1986, implying their importance. Epidermal growth factor receptor, EGFR, one of such factors, exists on cell surface and is activated by binding of its specific ligands. EGFR is a member of the receptor tyrosine kinase family
An Important Discovery on Mitochondrion Channels
It is known that dysfunction of protein transporters might cause diseases, such as cardiovascular or cancer. But with many studies, there is still no clear mechanism. In a recent study, researchers explored a channel complex and relevant membrane proteins. The channel complex, namely the
New Hormone Target Clues for Biopharmaceutical Companies
A new research found the effective effect of obesity-against of two hormones in gut, which might be an exciting news for drug companies and individuals who want to keep slim. The two hormones are PYY3-36 and PP. PYY3-36, or Peptide YY (peptide tyrosine tyrosine or pancreatic peptide YY3-36,
The Important Roles of MBNL Proteins in the Pluripotency of Stem Cells
Induced pluripotent stem cells are a vital research direction for the future academic and medical application. In past studies, scientists have paid much attention on the part of transcription, chromatin and non-coding RNA regulators of the pluripotency of embryonic stem (ES) cells.
Methionine Adenosyltransferase II alpha Related Researches and Products
Creative BioMart scientists innovate many MAT2A related products to support researchers’ work
Angewandte Chemie: The New Method to Make Therapeutic Proteins Last Longer
Nowadays therapeutic proteins are widely used to relieve sufferers from many conditions, such as cancers (Monoclonal antibodies, Interferons), heart disease and stroke (Enzymes, Blood factors), diabetes (Insulin), anaemia (Erythropoietin), haemophilia (Blood clotting factors) etc. and they show
Scientists Revealed How Genes Translate into Proteins on Molecular Level
In the picture, the green presents the messenger RNA, the brown presents the elongation factor EF-G, and the four sequential positions of transfer RNA as it moves from right to left during translocation (dark blue, light blue, red, and gray). Have you ever wondered how ribosome translates
The 3D Structure of RSV Has Been Revealed
The mention of Respiratory Syncytial Virus (RSV) reminds people of lung infection in children, which leads to more than 548 deaths every day. However, so far there is no relevant vaccine to prevent the virus due to under-investigation in some aspects. RSV causes flu-like symptoms in healthy
The Very Special Structure of an Enzyme
The left shows the single ring structure and the right shows the double ring structure or hexadecameric catenane As the above picture shows, scientists have found a very special shaped enzyme that has never been found previously in biology field. As early as in 2011, Microbiologist Mike has
The Method to Boost Protein Yields
Therapeutic proteins are now widely used for clinical purpose. Drugs based on proteins are increasingly important. Usually proteins from microbial cells are used to make drug, while with the demand of high efficacy and stability, animal cells are used to make more complex drugs. Proteins made
Cell: the “Protein backbone” of the Yeast Telosome
A model of the Rap1-Rif1-Rif2 Assembly at Telomeres Researchers have made a molecular, biochemical, and functional dissection on the protein backbone at the core of the yeast telosome. Repeated sequences form the genome as the sequence motif links sequence motif as well as binds proteins.
How Some Enzymes Involved in the Handling of Defective Proteins
The 2004 Nobel Prize in Chemistry went to scientists who found the protective program of ubiquitin-mediated protein degradation. Now a group of scientists found some enzymes that got involved in the degradation of defective proteins for the first time. It is well known that many cells are
Introduction to an Innovative Antibody Selection Method
It is reported in the Cell that researchers have developed a powerful innovative technique to find antibodies, especially therapeutic antibodies. A few years ago, the researchers developed a basic method to select antibodies that not only bind to a given target, but also have a desired
The Structural Secrets of Actin Nucleation was Found
Actin, a sturdy -like filament, helping cells maintain their shape, is an important factor for human. The filaments, named F-actin, were first discovered in late 1900s and been broadly studied since then. F-actin is composed by G-actin, which self-assemble end-to-end. But people are not clearly
Nppb-releasing TRPV1 “Takes Charge of” Itch Transmitting
TRPV1 cells, sensory neurons, have long been known that can detect itchy substances as well as other sensations, such as hot and pain, on the skin. But more specifically, it is unclear whether the neurons are unique responding to itch. In order to find answers, researchers did relevant
The Regulation Mechanism of RNA splicing Was Revealed
RNA splicing is a very complicated process which is carried out by spliceosome. Our spliceosomes are assembled from protein and RNA molecules, including 170 different proteins and five "small nuclear RNAs" (snRNAs). Currently we believed that certain snRNAs represent the tools with
Scientists Identified a New Role for EGFR
Protein encoded by epidermal growth factor receptor (EGFR) gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor.
Scientists Found a New Method to Understand Ion Channel Proteins
Photograph of integrated amplifiers. The well supporting the membrane and channel is noted in the figure. Ion channel are key regulators of cellular function. They are a critical group of important membrane protein drug targets and account for the activity of 10% of the currently marketed
CD44, CD47 and MET Have been Found Related to Initiation of Metastatic Cancer Cells
Circulating tumor cells (CTCs) are now treated as a biomarker for prognosis and people think the CTCs are connected to cancer metastasis. But there is no clear clue to clarify how CTCs affect patients. Some scientists thought only few CTCs will form secondary tumor in different organs as the
Scientists Reveal the Detailed Structure of Protein C4BP for Pharmaceutical Transport
Protein C4BP, the complement component 4 binding protein, is a part of our innate immune system which serves as the first countermeasures against invading pathogens. It could defend against bacterial in the blood. But in order to find reveal how exactly the protein acts on other molecules,
