Active Human Fatty Acid Binding Protein 1 (Liver) Reference Standard

• Cat.No.: FABP1-12H

Specification

• Description: FABP1 (Fatty acid binding protein1) encodes the fatty acid binding protein found in liver. FABP1 is composed of ten antiparallel β strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acid. This protein binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm; it may be involved in intracellular lipid transport and metabolism.
• Species: Human
• Form: Liquid
• Bio-activity: The level of L-FABP in the serum was quantified using ELISA.
• Usage: For research use only, not for diagnostic or therapeutic use.
• Quality Control Test: Generated from a human serum pool. This lot has been tested by standard laboratory procedures and found to be negative for HIV 1, HIV 2, Hepatitis B and Hepatitis C.
• Storage: Stored at -20 °C, 4 °C for less than seven days, frozen for greater than seven days.
• Concentration: 32.97 ng/ml
• Preservative: 0.1% sodium azide

Gene Information

• Gene Name: FABP1 fatty acid binding protein 1, liver [ Homo sapiens ]
• Official Symbol: FABP1
• Synonyms: FABP1; fatty acid binding protein 1, liver; fatty acid-binding protein, liver; L FABP; fatty acid-binding protein 1; liver-type fatty acid-binding protein; FABPL; L-FABP
• Gene ID: 2168
• mRNA Refseq: NM_001443
• Protein Refseq: NP_001434
• MIM: 134650
• UniProt ID: P07148
• Chromosome Location: 2p11
• Pathway: Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPAR signaling pathway, organism-specific biosystem; PPAR signaling pathway, conserved biosystem
• Function: bile acid binding; chromatin binding; drug binding; fatty acid binding; long-chain fatty acid transporter activity; phospholipid binding; transporter activity

Reviews

07/24/2019

One notable advantage of using the FABP1 protein is the outstanding technical support provided by its manufacturer.

05/28/2019

Its purity and functionality have been extensively tested, ensuring reliable and reproducible results in my research.

05/22/2019

The knowledgeable and responsive support team offers valuable assistance and expertise, making troubleshooting and problem-solving much more efficient.

Q&As

How is FABP1 linked to metabolic disorders?

Elevated levels of FABP1 are associated with metabolic disorders like obesity and insulin resistance, making it a potential indicator for these conditions.

How is FABP1 involved in fatty acid metabolism?

FABP1 binds to fatty acids, facilitating their transport and metabolism within liver cells.

Are there other organs where FABP1 is expressed?

While predominantly found in the liver, FABP1 is also expressed in the small intestine and kidney.

Can FABP1 be used for early detection of liver damage?

Yes, elevated FABP1 levels in blood or urine may indicate early stages of liver damage, enabling early intervention.

Are there genetic variations influencing FABP1 expression?

Genetic variations may contribute to differences in FABP1 expression, impacting an individual's susceptibility to certain diseases.