Active Recombinant Human CD3E&CD3D protein, His-Fc&Flag-Fc-tagged
Cat.No. : | CD3E&CD3D-2232H |
Product Overview : | Recombinant Human CD3E&CD3D protein(P04234-1 & P07766-1)(Met1-Ala105 & Met1-Asp126), fused with His-Fc&Flag-Fc tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | His-Fc&Flag-Fc |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its ability to bind OKT3-mIgG2a in a functional ELISA. |
Molecular Mass : | The recombinant heterodimer of human CD3D/CD3E consists of 687 (334+353) amino acids and predicts a molecular mass of 77.5 (37.7+39.8) kDa. It migrates as an approximately 44-54 KDa band in SDS-PAGE under reducing conditions due to glycosylation. |
Protein Length : | Met1-Ala105 & Met1-Asp126 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Products Types
◆ Recombinant Protein | ||
CD3E-144M | Recombinant Mouse CD3E Protein, Fc-tagged | +Inquiry |
CD3E-141H | Recombinant Human CD3E Protein, His-tagged | +Inquiry |
CD3E-140C | Recombinant Cynomolgus monkey CD3E Protein, His and Fc-tagged | +Inquiry |
CD3E-463H | Recombinant Human CD3E Protein (Met1-Asp126), His-tagged, Biotinylated | +Inquiry |
CD3E-138H | Recombinant Human CD3E Protein, His-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
CD3E-1602CCL | Recombinant Cynomolgus CD3E cell lysate | +Inquiry |
CD3E-1275HCL | Recombinant Human CD3E cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, CD3E levels and T-cell function can be monitored to evaluate the response to cancer immunotherapies like checkpoint inhibitors.
There are currently no approved therapies that directly target CD3E, but it is a target for research in developing immunotherapies and cancer treatments.
There may be ongoing clinical trials using CD3E-targeted therapies in the context of cancer and autoimmune diseases. It's important to check clinical trial databases for specific studies.
Yes, monitoring CD3E levels in HIV-infected individuals can provide valuable information about the progression of the disease and the effectiveness of antiretroviral therapy.
CD3E can be used in research to study T-cell responses in allergic conditions, helping to better understand and diagnose allergies.
Customer Reviews (3)
Write a reviewManufacturers with the capacity for bulk production can offer CD3E protein in larger quantities, which is advantageous for researchers working on large-scale experiments or collaborations.
bulk production often leads to economies of scale, making the CD3E protein more cost-effective for research budgets.
Manufacturers can actively seek collaborations and partnerships with researchers to develop new applications or optimize methodologies using CD3E protein.
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