Active Recombinant Human CSF2 Protein
Cat.No. : | CSF2-155C |
Product Overview : | Recombinant Human Granulocyte Macrophage Colony Stimulating Factor (rhGM-CSF) produced in P. pastoris a glycosylated polypeptide. A fully biologically active molecule, rhGM-CSF has a molecular mass of 26-32 kDa analyzed by SDS-PAGE and is obtained by proprietary refolding and chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Description : | Human Granulocyte Macrophage Colony Stimulating Factor (hGM-CSF), a hematopoietic growth factor, is mainly involved in granulopoiesis and monocytopoiesis. It is produced by T-cells and macrophages in response to antigens, and by endothelial cells and fibroblasts following induction of variouscytokines. A monomeric protein of 127 amino acidswith six glycosylation sites and two intra disulfide bonds, glycosylated and non-glycosylated hGM-CSFs show similar biological activities. Other than its connection to the growth and development of granulocytes and macrophages, it is also indispensable for the proliferation of erythroid and megakaryocytic cells. |
Source : | P. pastoris |
Species : | Human |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | ED50< 0.2 ng/mL, measured by proliferation assay of TF-1 cells, corresponding to a specific activity of > 56 units/mg. |
Molecular Mass : | 26-32kDa, observed by SDS-PAGE. |
AA Sequence : | MAPARSPSPSTQPWEHVNAIQEALR LLNLSRDTAAEMNETVEVISEMFDL QEPTCLQTRLELYKQGLRGSLTKLK GPLTMMASHYKQHCPPTPETSCATQ IITFESFKENLKDFLLVIPFDCWEP VQE |
Endotoxin : | < 1 EU/μg, determined by LAL method. |
Purity : | > 95 % as analyzed by SDS-PAGE. |
Storage : | Lyophilized recombinant human Granulocyte Macrophage Colony Stimulating Factor (rhGM-CSF) remains stable up to 12 months at -80 centigrade from date of receipt. Upon reconstitution, rhGM-CSF should be stable up to 4 weeks at 4 centigrade or up to 6 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against 10 mM PB, pH7.0. |
Reconstitution : | Reconstituted in ddH2O at 100 μg/mL. |
Gene Name : | CSF2 colony stimulating factor 2 (granulocyte-macrophage) [ Homo sapiens ] |
Official Symbol : | CSF2 |
Synonyms : | CSF2; colony stimulating factor 2 (granulocyte-macrophage); granulocyte-macrophage colony-stimulating factor; GM CSF; GMCSF; granulocyte macrophage colony stimulating factor; molgramostin; sargramostim; CSF; colony-stimulating factor; granulocyte-macrophage colony stimulating factor; MGC131935; MGC138897; |
Gene ID : | 1437 |
mRNA Refseq : | NM_000758 |
Protein Refseq : | NP_000749 |
MIM : | 138960 |
UniProt ID : | P04141 |
Products Types
◆ Recombinant Protein | ||
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Csf2-553R | Active Recombinant Rat Csf2 protein(Ala18-Lys144), hFc-tagged | +Inquiry |
CSF2-1968H | Active Recombinant Human CSF2 Protein | +Inquiry |
◆ Lysates | ||
CSF2-1008MCL | Recombinant Mouse CSF2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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