Active Recombinant Human ERBB4 Protein, GST-tagged
Cat.No. : | ERBB4-3450H |
Product Overview : | Human ERBB4 (NP_005226.1, 676 a.a. - 562 a.a.) full-length recombinant protein with GST tag expressed in Baculovirus infected Sf21 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Form : | Liquid |
Bio-activity : | The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorescence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000. Substrate: Srctide. ATP: 100 µM. |
Molecular Mass : | 99 kDa |
Purity : | 73 % by SDS-PAGE/CBB staining. |
Applications : | Functional Study SDS-PAGE |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol) |
Gene Name : | ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) [ Homo sapiens ] |
Official Symbol : | ERBB4 |
Synonyms : | ERBB4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v erb a avian erythroblastic leukemia viral oncogene homolog like 4; receptor tyrosine-protein kinase erbB-4; proto-oncogene-like protein c-ErbB-4; tyrosine kinase-type cell surface receptor HER4; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; HER4; p180erbB4; MGC138404; |
Gene ID : | 2066 |
mRNA Refseq : | NM_001042599 |
Protein Refseq : | NP_001036064 |
MIM : | 600543 |
UniProt ID : | Q15303 |
Products Types
◆ Recombinant Protein | ||
ERBB4-1791R | Recombinant Rat ERBB4 Protein, His (Fc)-Avi-tagged | +Inquiry |
ERBB4-2052H | Recombinant Human ERBB4 Protein, Fc/His-tagged | +Inquiry |
ERBB4-2116H | Recombinant Human ERBB4 Protein, MYC/DDK-tagged | +Inquiry |
ERBB4-04H | Active Recombinant Human ERBB4 Protein, hIgG/His-tagged | +Inquiry |
ERBB4-3451H | Recombinant Human ERBB4 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ERBB4-895RCL | Recombinant Rat ERBB4 cell lysate | +Inquiry |
ERBB4-001HCL | Recombinant Human ERBB4 cell lysate | +Inquiry |
ERBB4-1417MCL | Recombinant Mouse ERBB4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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