Active Recombinant Human Glypican 6, His-tagged
Cat.No. : | GPC6-5629H |
Product Overview : | RecombinantHuman GPC6 protein was expressed in Murine myeloma cell line. Asp24-Arg354& Ser355-Val527, with a C-terminal 6-His tag. |
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Cat. No. : | GPC6-5629H |
Description : | The glypicans(glypiated proteoglycans) are a small multigene family of GPI-linkedproteoglycans that likely play a key role in embryonic morphogenesis. Thereare six known mammalian glypicans. They all share a common-sized protein coreof 60-70 kDa, an N-terminus which likely forms a compact globular domain, 14conserved cysteines that form multiple intrachain disulfide bonds, and anumber of C-terminal N-and O-linked carbohydrate attachment sites. Based onexon organization and the location of O-linked glycosylation sites, at leasttwo subfamilies of glypicans are known, with one subfamily containingglypicans-1, 2, 4, and 6, and another subfamily containing glypicans-3 and 5. |
Source : | Mammalian cells |
Form : | Lyophilized from a0.2 um filtered solution in PBS. |
N-terminalSequence : | Asp24 & Ser355 |
MolecularWeight : | 38 kDa and 20 kDa |
Activity : | Measuredby its binding ability in a functional ELISA. When biotinylated rmWnt-3a (0.5μg/mL, 100 μL/well) is captured on streptavidin-coated plate, rhGlypican-6binds with an apparent KD < 10 nM. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 38 kDaand 27-29 kDa, reducing conditions. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstituteat 100μg/mL in PBS. |
Storage : | Use a manual defrost freezer and avoid repeated freezethawcycles. 12months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °Cunder sterile conditions after reconstitution. 3 months, -20 to -70 °C understerile conditions after reconstitution. |
Gene Name : | GPC6 glypican 6 [ Homosapiens ] |
Official Symbol : | GPC6 |
Synonyms : | GPC6; glypican 6;OMIMD1; glypican-6;glypican proteoglycan 6 |
Gene ID : | 10082 |
mRNA Refseq : | NM_005708 |
Protein Refseq : | NP_005699 |
MIM : | 604404 |
UniProt ID : | Q9Y625 |
Chromosome Location : | 13q32 |
Function : | heparan sulfateproteoglycan binding |
Products Types
◆ Recombinant Protein | ||
GPC6-1403H | Recombinant Human GPC6 Protein (24-529 aa), His-tagged | +Inquiry |
GPC6-3058H | Recombinant Human GPC6 Protein, His (Fc)-Avi-tagged | +Inquiry |
GPC6-2987H | Recombinant Human GPC6 protein, His-SUMO-tagged | +Inquiry |
GPC6-13417H | Recombinant Human GPC6, His-tagged | +Inquiry |
◆ Lysates | ||
GPC6-5811HCL | Recombinant Human GPC6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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