Active Recombinant Human HAVCR2, HIgG1 Fc-tagged
Cat.No. : | HAVCR2-219H |
Product Overview : | The extracellular domain of human Tim-3 (NP_116171.3) (Ser22-Arg200) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins.CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokinesecretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-typehypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infectionsand the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein thatregulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotesimmunological tolerance. |
Source : | CHO cells |
Species : | Human |
Tag : | HIgG1 Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its binding ability in a functional ELISA. |
Molecular Mass : | 48 KDa (monomer) |
AA Sequence : | Ser22-Arg200 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | HAVCR2 hepatitis A virus cellular receptor 2 [ Homo sapiens ] |
Official Symbol : | HAVCR2 |
Synonyms : | HAVCR2; hepatitis A virus cellular receptor 2; FLJ14428; Tim 3; TIM3; TIMD3; kidney injury molecule-3; T-cell membrane protein 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain-containing protein 3; KIM-3; Tim-3; TIMD-3; HAVcr-2; |
Gene ID : | 84868 |
mRNA Refseq : | NM_032782 |
Protein Refseq : | NP_116171 |
MIM : | 606652 |
UniProt ID : | Q8TDQ0 |
Chromosome Location : | 5q34 |
Products Types
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HAVCR2-734C | Recombinant Cynomolgus monkey HAVCR2 Protein, Fc-tagged | +Inquiry |
HAVCR2-111H | Recombinant Human HAVCR2 Protein (ECD), His-tagged(C-ter) | +Inquiry |
HAVCR2-110H | Recombinant Human HAVCR2 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
Havcr2-138M | Recombinant Mouse Havcr2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
HAVCR2-995MCL | Recombinant Mouse HAVCR2 cell lysate | +Inquiry |
HAVCR2-001CCL | Recombinant Cynomolgus HAVCR2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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