Active Recombinant Human Histone Deacetylase 3, His GST-tagged
Cat.No. : | HDAC3-394H |
Product Overview : | Full Length Human HDAC3– Class I, 53kD with his His & GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | HDAC3-394H |
Description : | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. |
Source : | HDAC3 was cloned from human brain cDNA and expressed in insect cells using a baculoviral expression system. |
Purity : | Purified, active enzyme. |
Purification Procedure : | Ni2+ Affinity Column & Glutathione |
Activity : | 1000 units per vial. 1 unit is defined as the amount of enzyme that will convert 1picomole per minute per ug of protein at pH8 at 30°C. |
Stability/Shelf-life : | >6 months from date of shipment |
Buffer Composition : | 25mM Tris pH8, 120mM NaCl, 0.05% Tween-20 & 40% Glycerol. |
Storage : | –80°C |
Gene Name : | HDAC3 histone deacetylase 3 [ Homo sapiens ] |
Synonyms : | HDAC3; RPD3; HD3; RPD3-2; histone deacetylase 3; EC 3.5.1.98; SMAP45. |
Gene ID : | 8841 |
mRNA Refseq : | NM_003883 |
Protein Refseq : | NP_003874 |
MIM : | 605166 |
UniProt ID : | O15379 |
Chromosome Location : | 5q31 |
Pathway : | Signalling by NGF |
Function : | DNA binding; histone deacetylase activity; hydrolase activity; transcription factor binding |
Products Types
◆ Recombinant Protein | ||
HDAC3-3099H | Recombinant Human HDAC3 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC3-2235H | Recombinant Human HDAC3 Protein, His-tagged | +Inquiry |
HDAC3-46H | Recombinant Human HDAC3 Protein, His-tagged | +Inquiry |
Hdac3-1103M | Recombinant Mouse Hdac3 Protein, MYC/DDK-tagged | +Inquiry |
HDAC3-4643H | Recombinant Human HDAC3 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
HDAC3-572HCL | Recombinant Human HDAC3 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2254 | HDAC3 Activity Fluorometric Assay Kit | +Inquiry |
Kit-2282 | HDAC3 Immunoprecipitation (IP) & Activity Assay Kit | +Inquiry |
Kit-1739 | HDAC3 Kinetic Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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