Active Recombinant Human MMP13 Protein
Cat.No. : | MMP13-5420H |
Product Overview : | Human MMP13 (104 a.a. - 274 a.a.) partial recombinant protein expressed in Escherichia coli. |
- Specification
- Gene Information
- Related Products
Description : | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq |
Source : | E. coli |
Species : | Human |
Form : | Liquid |
Bio-activity : | > 500 mU/mg |
Molecular Mass : | 19.5 kDa |
AA Sequence : | YNVFPRTLKWSKMNLTYRIVNYTPD MTHSEVEKAFKKAFKVWSDVTPLNF TRLHDGIADIMISFGIKEHGDFYPF DGPSGLLAHAFPPGPNYGGDAHFDD DETWTSSSKGYNLFLVAAHEFGHSL GLDHSKDPGALMFPIYTYTGKSHFM LPDDDVQGIQSLYGPGDEDPN |
Purity : | > 90% by SDS-PAGE |
Applications : | Functional Study SDS-PAGE |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Concentration : | 0.2 mg/mL |
Storage Buffer : | In 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, pH 7.5 |
Gene Name : | MMP13 matrix metallopeptidase 13 (collagenase 3) [ Homo sapiens ] |
Official Symbol : | MMP13 |
Synonyms : | MMP13; matrix metallopeptidase 13 (collagenase 3); matrix metalloproteinase 13 (collagenase 3); collagenase 3; CLG3; MMP-13; MANDP1; |
Gene ID : | 4322 |
mRNA Refseq : | NM_002427 |
Protein Refseq : | NP_002418 |
MIM : | 600108 |
UniProt ID : | P45452 |
Products Types
◆ Recombinant Protein | ||
MMP13-01H | Active Recombinant Human MMP13 (F175D) Protein | +Inquiry |
MMP13-0833H | Recombinant Human MMP13 Protein (E103-N274), His tagged | +Inquiry |
MMP13-2765H | Recombinant Human MMP13 protein(361-430 aa), C-His-tagged | +Inquiry |
MMP13-0832H | Recombinant Human MMP13 Protein (E103-N274), Tag Free | +Inquiry |
MMP13-2045D | Recombinant Dog MMP13 Protein (28-478 aa), His-SUMO-tagged | +Inquiry |
◆ Lysates | ||
MMP13-4280HCL | Recombinant Human MMP13 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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