Active Recombinant Human NCOR1/HDAC3 Protein, GST-tagged
Cat.No. : | NCOR1-16H |
Product Overview : | Recombinant Human NCOR1/HDAC3(NCOR1 amino acids 397-503) fused with GST tag was expressed in Insect cells. |
- Specification
- Gene Information
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Description : | Approximately 1:1 stoichiometric complex of recombinant human HDAC3 (histone deacetylase 3) with a GST fusion protein comprising the Deacetylase Activation Domain (DAD) of human NCOR1 (amino acids 397-503; SANT1 domain plus amino flanking residues). Produced by coexpression of HDAC3 with a GST-NCOR1(DAD) construct in an insect cell system, the complex displays ~100-fold higher deacetylase activity than isolated HDAC3 (based on equal weights HDAC3 assayed at a saturating concentration (100µM) of a fluorogenic peptide substrate p53 379-382, K(Ac)382).This HDAC3 preparation is active with various fluorogenic peptide substrates, including FLUOR DE LYS® Substrate and FLUOR DE LYS®-SIRT1 (p53 379-382, K(Ac)382). |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Form : | Liquid. In 50mM TRIS, pH 8.0, 138 mM NaCl and 10% glycerol. |
Bio-activity : | ≥150 U/µg. |
Molecular Mass : | 49/40 kDa |
Protein length : | NCOR1 amino acids 397-503 |
Purity : | ≥90% (SDS-PAGE) |
Storage : | Store at -80 centigrade |
Gene Name : | NCOR1 nuclear receptor corepressor 1 [ Homo sapiens ] |
Official Symbol : | NCOR1 |
Synonyms : | NCOR1; nuclear receptor corepressor 1; nuclear receptor co repressor 1; hCIT529I10; hN CoR; KIAA1047; MGC104216; N CoR; thyroid hormone and retinoic acid receptor associated corepressor 1; TRAC1; nuclear receptor co-repressor 1; thyroid hormone- and retinoic acid receptor-associated corepressor 1; N-CoR; N-CoR1; hN-CoR; |
Gene ID : | 9611 |
mRNA Refseq : | NM_001190438 |
Protein Refseq : | NP_001177367 |
MIM : | 600849 |
UniProt ID : | O75376 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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