Active Recombinant Mouse Il17b Protein (His21-Phe180), C-His tagged, Animal-free, Carrier-free

• Cat.No.: Il17b-254M
• Product Overview: Recombinant Mouse Il17b Protein (His21-Phe180) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Description: Interleukin 17B (IL-17B) predicts a molecular mass of 20.4 kDa, is expressed in several peripheral tissues and immune tissues. In contrast to the high level of IL-6 secretion stimulated by IL-17A, IL-17B failed to induce IL-6 secretion in fibroblasts; however, it significantly enhanced the TNF-α-induced production of G-CSF and IL-6 in the fibroblasts.
• Source: E. coli
• Species: Mouse
• Tag: C-His
• Form: Lyophilized
• Bio-activity: Measure by its ability to induce IL-8 secretion in HepG2 cells. The ED50 for this effect is < 1.5 ng/mL.
• Molecular Mass: The protein has a calculated MW of 18.99 kDa.
  The protein migrates as 17-25 kDa under reducing condition (SDS-PAGE analysis).
• Protein Length: His21-Phe180
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: Il17b interleukin 17B [ Mus musculus (house mouse) ]
• Official Symbol: Il17b
• Synonyms: IL17B; interleukin 17B; interleukin-17B; IL-17B; cytokine CX1; cytokine-like protein ZCYTO7; gene for cytokine-like protein; neuronal interleukin-17-related factor; Zcyto7; 1110006O16Rik; 1700006N07Rik
• Gene ID: 56069
• mRNA Refseq: NM_019508
• Protein Refseq: NP_062381
• UniProt ID: Q9QXT6