Active Recombinant Rat Csf1 Protein (155 aa)
Cat.No. : | Csf1-333C |
Product Overview : | Recombinant Rat Macrophage Colony Stimulating Factor (M-CSF) produced in E. coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 155 amino acids each. A fully biologically active molecule, rrM-CSF has a molecular mass of 28 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Description : | Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells. Interaction of M-CSF with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of several types of cancer, including breast and endometrial cancer. |
Source : | E. coli |
Species : | Rat |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | ED50 < 5 ng/mL, measured in a cell proliferation assay using Murine M-NFS-60 cells, corresponding to a specific activity of > 2 × 10^5 units/mg. |
Molecular Mass : | 28 kDa, observed by reducing SDS-PAGE. |
Protein Length : | 155 |
AA Sequence : | MEVSEHCSHMIGNGHLQILQQLIDS QMETACLIEYKFVDQEQLDDPVCYL KKAFVLVQVIIEETMRFKDNTPNAN ATERLQELSMKLNSCFIKDYKEQNE ACVQTYKESPLRLLEKIKNFFNETK NFLEKDWNIFSKNCNDSLAKCSSRD VVTKP |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 95% as analyzed by SDS-PAGE. |
Storage : | Lyophilized recombinant Rat Macrophage Colony Stimulating Factor(M-CSF) remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, Rat M-CSF should be stable up to 1 week at 4 centigrade or up to 3 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against 50mM Tris, 150mM NaCl, pH 8.0. |
Reconstitution : | Reconstituted in ddH2O at 100 μg/mL. |
Gene Name : | Csf1 colony stimulating factor 1 (macrophage) [ Rattus norvegicus ] |
Official Symbol : | Csf1 |
Synonyms : | CSF1; colony stimulating factor 1 (macrophage); macrophage colony-stimulating factor 1; MCSF; CSF-1; |
Gene ID : | 78965 |
mRNA Refseq : | NM_023981 |
Protein Refseq : | NP_076471 |
UniProt ID : | Q8JZQ0 |
Products Types
◆ Recombinant Protein | ||
Csf1-1107M | Recombinant Mouse Csf1 Protein, His-tagged | +Inquiry |
CSF1-1962H | Recombinant Human CSF1 Protein, GST-tagged | +Inquiry |
Csf1-222C | Active Recombinant Mouse Csf1 Protein | +Inquiry |
CSF1-41H | Active Recombinant Human CSF1 Protein, Animal Free | +Inquiry |
Csf1-221C | Active Recombinant Rat Csf1 Protein | +Inquiry |
◆ Lysates | ||
CSF1-001MCL | Recombinant Mouse CSF1 cell lysate | +Inquiry |
CSF1-1934HCL | Recombinant Human CSF1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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