| Cat. No. : |
spa-1286S |
| Description : |
Protein A is a cell wall protein deriving from Staphylococcus aureus which exhibits unique binding properties for IgG from a variety of mammalian species and for some IgM and IgA as well. It binds with the Fc region of immunoglobulins through interaction with the heavy chain. It couples to a wide variety of reporter molecules including fluorescent dyes, enzyme markers, biotin, colloidal gold and radioactive iodine without affecting the antibody binding site. Recombinant Protein A was developed to increase the specificity of the molecule for IgG and is widely used both in research and bioprocessing. The recombinant protein A is produced by expressing a modified protein A gene in E.coli. A specific purification process with strict quality control was taken to get the recombinant protein A with the purity of more than 98% , no human IgG affinity step is used during validated fermentation and purification and devoid of bacterial contaminant found normally in native Protein A. (Free of Staphylococcus endotoxins and hemolysin). |
| Source : |
Escherichia Coli. |
| Physical Appearance : |
Sterile Filtered clear colorless solution. |
| Formulation : |
The protein solution contains no additives. |
| Activity : |
Greater than 95.0% binding activity to human IgG. |
| Purity : |
Greater than 98.0% as determined by RP-HPLC. |
| Stability : |
SPA should be stored at -20°C. |
