Native Porcine Coagulation Factor II (thrombin)

• Cat.No.: F2-5402P
• Product Overview: Native human F2 was expressed in Porcine.

Specification

• Description: F2 is aserine protease protein that in humans is encoded by the F2 gene. Prothrombin(coagulation factor II) is proteolytically cleaved to form thrombin in thefirst step of the coagulation cascade, which ultimately results in thestemming of blood loss. F2 in turn acts as a serine protease that convertssoluble fibrinogen into insoluble strands of fibrin, as well as catalyzingmany other coagulation-related reactions.
• Source: Porcine
• Species: Porcine
• Form: 50:50 Glycerol: Water.
• Molecular Mass: 362.0 kDa
• Storage: Below -20°C.

Gene Information

• Gene Name: F2 coagulation factor II (thrombin) [ Sus scrofa ]
• Official Symbol: F2
• Synonyms: prothrombin; thrombin
• Gene ID: 100144442
• mRNA Refseq: NM_001122985
• Protein Refseq: NP_001116457
• UniProt ID: Q19AZ8
• Chromosome Location: 2; 2
• Pathway: Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem
• Function: calcium ion binding; serine-type endopeptidase activity