"IL1RN" Related Products

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Mouse Anti-IL1RN Monoclonal Antibody

Cat.No.: DMABT-H18692
Product Overview: Mouse Anti-IL1RN Monoclonal Antibody
Antigen Description: Interleukin-1 receptor antagonist (IL-1RA) is composed of three isoforms, one secreted (sIL-1Ralpha/IL-1Ralpha1), two intracellular (IL-1Ralpha2/IL-1Ralpha3) and produced by monocytes, tissue macrophages, Langerhans cells, dendritic cells, T and B cells, natural killer (NK) cells, large granular lymphocytes (LGL), vascular endothelium, smooth muscle, fibroblasts, thymic epithelia, astrocytes, microglia, glioma cells, keratinocytes, and chondrocytes. It is upregulated by IL-1beta, IL-4, IL-6 and downregulated by glucocorticoids.
Target: IL1RN
Immunogen: Recombinant human IL-1 receptor antagonist
Host: Mouse
Isotype: IgG1
species: Human
Clone: KL2SB-2
Conjugation: N/A
Applications: ELISA
Preparation: The antibody was purified by affinity chromatography.
Usage recommendation: Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 4-6 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4 °C.
Size: 50 μg;500 μg
Gene Name: IL1RN interleukin2receptor antagonist [ Homo sapiens ]
Official Symbol: IL1RN
Synonyms: IL1RN; interleukin2receptor antagonist; interleukin-1 receptor antagonist protein; ICIL 1RA; IL 1RN; IL1F3; IL1RA; interleukin2receptor antagonist protein; intracellular interleukin2receptor antagonist; IRAP; MGC10430; IL1 inhibitor; IL1RN (IL1F3); type II interleukin-1 receptor antagonist; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); DIRA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA;
Gene ID: 3557
mRNA Refseq: NM_000577
Protein Refseq: NP_000568
MIM: 147679
UniProt ID: P18510
Chromosome Location: 2q14.2
Pathway: Cytokine Signaling in Immune system, organism-specific biosystem; IL-1 Signaling Pathway, organism-specific biosystem; IL1-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem; Signaling by Interleukins, organism-specific biosystem;
Function: interleukin-1 Type I receptor antagonist activity; interleukin-1 Type II receptor antagonist activity; interleukin-1 receptor antagonist activity; interleukin-1 receptor antagonist activity; interleukin-1 receptor binding; interleukin-1, Type I receptor binding; interleukin-1, Type II receptor binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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