Active Recombinant Human TNFSF12
Cat.No. : | TNFSF12-8461H |
Product Overview : | The recombinant human TWEAK is a 17.0 kDa protein, comprising the TNF-like extraCellular domain of TWEAK and was expressed in E. coli |
- Specification
- Gene Information
- Related Products
Description : | Human TWEAK is a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. TWEAK, like many other members of the TNF family, is able to induce interleukin-8 synthesis in a number of cell lines. |
Source : | E. coli |
Species : | Human |
Form : | Sterile filtered and lyophilized from 10 mM Sodium Phosphate, pH 7.5 + 0.1 M L-Arg. |
Bio-activity : | The ED?? as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 10 ng/ml. |
Molecular Mass : | 17.0 kDa |
Endotoxin : | <0.1>0.1> |
Purity : | ≥98% by SDS - PAGE; ≥98% by HPLC |
Storage : | The lyophilized human TWEAK is best-stored desiccated below 0℃. Reconstituted TWEAK should be stored in working aliquots at -20℃. |
Reconstitution : | Reconstitute in 10 mM Sodium Phosphate (pH 7.5) to a concentration of 1 mg/ml. This solution can then be diluted into other aqueous buffers |
Shipping : | Blue ice |
Gene Name : | TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 [ Homo sapiens ] |
Official Symbol : | TNFSF12? |
Synonyms : | TNFSF12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand superfamily member 12; APO3L; DR3LG; TWEAK; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis; MGC20669; MGC129581; |
Gene ID : | 8742 |
mRNA Refseq : | NM_003809 |
Protein Refseq : | NP_003800 |
MIM : | 602695 |
UniProt ID : | O43508 |
Chromosome Location : | 17p13.1 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Gene Expression, organism-specific biosystem; Regulation of mRNA Stability by Proteins that Bind AU-rich Elements, organism-specific biosystem; Stabilization of mRNA by HuR, organism-specific biosystem; |
Function : | cytokine activity; cytokine activity; protein binding; receptor binding; tumor necrosis factor receptor binding; |
Products Types
◆ Recombinant Protein | ||
TNFSF12-01H | Recombinant Human TNFSF12 Protein, His/FLAG-tagged | +Inquiry |
TNFSF12-305H | Active Recombinant Human TNFSF12 Protein (Lys56-His249), C-His tagged, Animal-free, Carrier-free | +Inquiry |
Tnfsf12-86M | Active Recombinant Mouse Tnfsf12 Protein (His110-His249), C-His tagged, Animal-free, Carrier-free | +Inquiry |
TNFSF12-200T | Active Recombinant Human TNFSF12 Protein | +Inquiry |
TNFSF12-9483M | Recombinant Mouse TNFSF12 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TNFSF12-1155CCL | Recombinant Cynomolgus TNFSF12 cell lysate | +Inquiry |
TNFSF12-1204RCL | Recombinant Rat TNFSF12 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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