Recombinant human TGFB2, Active
| Cat.No. : | TGFB2-1566H |
| Product Overview : | Recombinant human TGF-β2 is a 27.08 kDa protein composed of two identical 118 amino acid polypeptide chains linked by a single disulphide bond. |
- Specification
- Gene Information
- Related Products
| Description : | Recombinant human TGF-β2 is a 27.08 kDa protein composed of two identical 118 amino acid peptide chains linked by a single disulphide bond. Transforming growth factor–β is a family of five related cytokines that have been shown on a wide variety of normal and neoplastic cells, indicating the importance of these homo-dimmer proteins as multi-functional regulators of cellular activity. The three mammalian isoforms of TGF-β (TGF-β1, TGF-β2 and TGF-β3) signal through the same receptor and elicit similar biological responses. They are involved in physiological processes as embryogenesis, tissue remodelling and wound healing. |
| Source : | Human recombinant protein expressed in Nicotiana benthamiana. It is produced by transient expression in non-transgenic plants. This product contains no animal–derived components or impurities. Animal Free product. |
| Species : | Human |
| Form : | Recombinant human TGF-b2 is lyophilized from a Tris HCl 0.05M buffer at pH 7.4. |
| Molecular Mass : | 27.08 kDa |
| AA Sequence : | HHHHHHALDAAYCFRNVQDNCCLRP LYIDFKRDLGWKWIHEPKGYNANFC AGACPYLWSSDTQHSRVLSLYNTIN PEASASPCCVSQDLEPLTILYYIGK TPKIEQLSNMIVKSCKCS |
| Endotoxin : | < 0.04 eu/μg protein (lal> |
| Purity : | >97% by SDS-PAGE gel |
| Storage : | This lyophilized preparation is stable at 2-8o C for short term, long storage it should be kept at -20oC. Reconstituted protein should be stored in working aliquots at –20°C. Repeated freezing and thawing is not recommended. |
| Reconstitution : | Centrifuge vial before opening. Lyophilized protein should be reconstituted in water to a concentration of 25ng/ul. At higher concentration the solubility may be reduced and multimers generated. |
| Gene Name : | TGFB2 transforming growth factor, beta 2 [ Homo sapiens ] |
| Official Symbol : | TGFB2 |
| Synonyms : | TGFB2; transforming growth factor, beta 2; transforming growth factor beta-2; G-TSF; cetermin; polyergin; BSC-1 cell growth inhibitor; glioblastoma-derived T-cell suppressor factor; TGF-beta2; MGC116892; |
| Gene ID : | 7042 |
| mRNA Refseq : | NM_001135599 |
| Protein Refseq : | NP_001129071 |
| MIM : | 190220 |
| UniProt ID : | P61812 |
| Chromosome Location : | 1q41 |
| Pathway : | ATF-2 transcription factor network, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; |
| Function : | beta-amyloid binding; cytokine activity; growth factor activity; protein binding; contributes_to protein binding; protein heterodimerization activity; protein homodimerization activity; receptor binding; receptor signaling protein serine/threonine kinase |
Products Types
| ◆ Lysates | ||
| TGFB2-1119HCL | Recombinant Human TGFB2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket
