Recombinant Mouse IL-13
Cat.No. : | IL13-60M |
Product Overview : | Mouse IL-13 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin 13 (IL-13) is secreted by many cell types, but especially T helper type 2 (Th2) cells. IL-13 is an important mediator of allergic inflammation and disease. In addition to effects on immune cells, IL-13 is implicated as a central mediator of the physiologic changes induced by allergic inflammation in many tissues. The functions of IL-13 overlap considerably with those of IL-4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL-4. Thus, although IL-13 can induce immunoglobulin E (IgE) secretion from activated human B cells, deletion of IL-13 from mice does not markedly affect either Th2 cell development or antigen-specific IgE responses induced by potent allergens. In comparison, deletion of IL-4 abrogates these responses. Thus, rather than a lymphoid cytokine, IL-13 acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function. |
Source : | Yeast |
Species : | Mouse |
Form : | Lyophilized |
Molecular Mass : | 12.2 kDa |
AA Sequence : | GPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F (111) |
Applications : | The Mouse IL-13 protein can be used in cell culture, as an IL-13 ELISA Standard, and as a Western Blot Control. |
Storage : | -20 C |
Gene Name : | Il13 interleukin 13 [ Mus musculus ] |
Official Symbol : | IL13 |
Synonyms : | IL13; interleukin 13; interleukin-13; T-cell activation protein P600; Il-13; |
Gene ID : | 16163 |
mRNA Refseq : | NM_008355 |
Protein Refseq : | NP_032381 |
Pathway : | Asthma, organism-specific biosystem; Asthma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytokines and Inflammatory Response (BioCarta), organism-specific biosystem; Fc epsilon RI signaling pathway, organism-specific biosystem; Fc epsilon RI signaling pathway, conserved biosystem; |
Function : | cytokine activity; cytokine receptor binding; interleukin-13 receptor binding; |
Products Types
◆ Recombinant Protein | ||
IL13-504H | Recombinant Human IL13 Protein, Fc-tagged | +Inquiry |
IL13-1660R | Recombinant Rhesus monkey IL13 Protein, His-tagged | +Inquiry |
Il13-089M | Recombinant Mouse Il13 Protein | +Inquiry |
Il13-088M | Recombinant Mouse Il13 Protein | +Inquiry |
IL13-1002H | Recombinant Human IL13 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IL13-2922HCL | Recombinant Human IL13 cell lysate | +Inquiry |
IL13-001HCL | Recombinant Human IL13 cell lysate | +Inquiry |
IL13-1894CCL | Recombinant Cynomolgus IL13 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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